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Effect of preservative free fluoroquinolones on human corneal epithelial cells in vitro

Fluoroquinolones, including second generation (ofloxacin and ciprofloxacin), third generation (levofloxacin and tosufloxacin) and fourth generation (gatifloxacin and moxifloxacin), are a group of bactericidal agents used to treat multiple ocular infections. The third and fourth generation fluoroquinolones have enhanced Gram-positive activity...

Tackling diabetic retinopathy globally through the VISION 2020 LINKS Diabetic Retinopathy Network

It is abundantly clear that the burden of diabetes is rapidly increasing, as there are now 415 million adults with diabetes in the world, with a projected rise to 642 million by 2040 [1]. This equates to 1 in 10...

Optic nerve head perfusion response to reduced blood pressure and increased intraocular pressure

The purpose of this prospective study was to test the hypothesis that blood flow autoregulation in the optic nerve head has less reserve to maintain normal blood flow where there is a blood pressure induced decrease in ocular perfusion pressure...

Meibomian gland alteration in patients with primary chronic dacryocystitis: An in vivo confocal microscopy study

Chronic dacryocystitis affects tear film functionality and can predispose to ocular surface disease, however the specific effect of chronic dacryocystitis on meibomian gland function has not been studied. This group therefore performed in vivo confocal microscopy in 28 patients’ eyes...

Resurfacing the ocular surface

The ocular surface (OS) is an anatomical and functional unit made of the tear film, the conjunctival, limbal and corneal epithelium, the lacrimal, mucous and meibomian glands and the lids and blink reflex. The tear film is composed of a...

Residual esotropia surgery comparisons

The aim was to compare lateral rectus resection and plication methods in patients with residual esotropia for postoperative success rate, dose response, ipsilateral medial rectus limitations and reoperation. The study included 57 patients (31 female, 26 male) with 27 plication...

Aug/Sep 2015 Quiz 1

History A 60-year-old woman was referred to ophthalmology with a suspected left eye choroidal naevus. Visual acuity was unaffected in both eyes and she was asymptomatic. Ocular history and medical history were unremarkable. Questions Figure 1: Fundus photograph. 1. What...

“Robot performs cataract surgery on patient!”

Simerdip Kaur takes a look at the latest ophthalmology-related news stories and asks which are scientific reality and which are ‘fake news’. Headline: “Robot performs cataract surgery on patient!” Twenty-five years ago when Eye News launched, a news headline such...

Effects of ML4 on the eye

Mucolipidosis type IV (ML4) is an autosomal recessive lysosomal storage disease and is caused by variants of the MC0LN1 gene. It often presents in young individuals with eye and ocular adnexa issues. The authors present a case report and literature...

Comic leaflets: an innovative method of patient education

Nowadays almost everyone has been exposed to comics, especially during childhood. In a way, this is a natural form of progression from children’s story books, which also contain words and pictures. This exposure has helped us to develop the graphic...

Mastering Monovision with Professor Graham Barrett and Mr Alastair Stuart

Professor Graham Barrett, creator of RayOne EMV, joins Mr Alastair Stuart, Medical Director of Optegra UK, to discuss why he frequently selects this lens for patients in Rayner’s Peer2Peer podcast series. Mr Stuart shares insights on patient selection, calculations, and...

Patient care a family affair at Newcastle-Under-Lyme eye hospital

With Mother’s Day just around the corner, mother and daughter Lisa Moors and Hannah Young won’t have to wait until next Sunday to spend time together - the pair work side-by-side, caring for hundreds of cataract surgery patients each week...