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The fragile p-value

Abdus Samad Ansari explores the limitation of the p-value and the application of the fragility index in clinical trials. Clinical trials and tribulations? The restoration of vision or more purely the gift of sight is an aspect of care that...

Change in psychosocial, quality of life and anxiety after strabismus surgery

The authors aimed to define the impact of surgical correction on psychiatric problems, health-related quality of life and anxiety levels in children and their parents. This was a cross-sectional study of 39 children with strabismus and their parents. All children...

Subthreshold micropulse laser treatment in chronic central serous chorioretinopathy

This retrospective study was conducted to assess the treatment of 38 patients of chronic central serous chorioretinopathy with a 577-nm subthreshold micropulse laser (SML) Supra Scan Quantel Medical. Eighteen patients of these had persistent subretinal fluid (SRF) after photodynamic therapy....

Corneal crosslinking in pellucid marginal degeneration

Fourteen studies were included in this first review examining the use of corneal-crosslinking (CXL) to treat pellucid marginal degeneration (PMD). PMD is a bilateral, non-inflammatory corneal thinning disorder characterised by inferior peripheral corneal thinning 1-3mm from the limbus in the...

ANGPTL-4 inhibition reduces inflammation in diabetic retinopathy

Diabetic retinopathy (DR) is the most common cause of blindness in working-age humans, and numbers are rising due to increased cases of type 2 diabetes (T2D). T2D is associated with increased obesity and dyslipidaemia, which is a major risk factor...

#KnowYourDrops: breaking down barriers to poor compliance

Award-winning* #KnowYourDrops eye drop compliance campaign helps patients for World Glaucoma Week to achieve medicines optimisation in ophthalmology. The #KnowYourDrops campaign is fast becoming an internationally recognised model to help support healthcare professionals, with the provision of better tailored ophthalmic...

Causes of abnormal head postures – literature review

Yadegari reports a narrative literature review for abnormal head postures (AHPs) with discussion on different causes. This review summarises the control of a normal head posture before discussing differences of ocular vs non-ocular AHPs. Ocular AHPs may be adopted to...

Shifting the paradigm of managing patients in medical retina: how real-world data can help us to improve clinical practice

The ophthalmic subspecialty of ‘medical retina’ has undergone dramatic changes in recent years. With the introduction of ranibizumab (Lucentis, Novartis), a specialty formerly dominated by laser-based therapies has been transformed to become, in large part, pharmacotherapy-based. To date, these pharmacotherapies...

A brief history of colour vision

Andrew Want takes a look at how colour vision has evolved in humans and animals and how it differs across species. Colour vision is something that we often take for granted, but it has become so intrinsic to the way...

Kevin Gutsell became president of the Association of British Dispensing Opticians

Kevin Gutsell FBDO (Hons) SLD became president of the Association of British Dispensing Opticians (ABDO) during a ceremony held on Thursday 9 May at the ABDO National Resources Centre (NRC) in Birmingham.

The role of spectral-domain OCT RNFL in revealing a pituitary adenoma with atypical visual fields

Pituitary adenomas classically cause bitemporal hemianopia by compressing the optic chiasm. However, in some cases, the pattern of visual field loss may be atypical and mimic homonymous hemianopia, depending on the direction and extent of tumour expansion. Spectral-domain optical coherence...

Effects of topical anaesthetic on intraocular pressure

This prospective interventional study assessed the effects of repeated intraocular pressure (IOP) using Goldmann applanation tonometry and applanation resonance tonometry in six volunteers. Previous literature supports IOP reduction using repeated applanation tonometry. Repeated IOP measures were taken alternately on 12...