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Ophthalmic mentors: Professor Carrie MacEwen

Caroline (Carrie) MacEwen is a Consultant Ophthalmologist at Ninewells Hospital and Medical School, Dundee, and Head of the Ophthalmology Department at the University of Dundee (Honorary Professor). She trained in Glasgow, Dundee and London. Carrie took over as President of...

Leber’s hereditary optic neuropathy: from lab to clinic

Leber’s hereditary optic neuropathy (LHON) was the first clinically described mitochondrial disorder (1871). This article reviews the pathophysiology and clinical features of LHON with a focus on translational research. G11778A is currently the most common mutation worldwide and is associated...

Scottish Glaucoma Symposium 2024

by Nivi Aravind, Y5 Medical Student, University of Edinburgh, UK. The 22nd Scottish Glaucoma Symposium enlivened the prestigious Royal College of Surgeons in Edinburgh on 21 June in what was a delightful meeting of minds. The day’s programme was impeccably...

Nicotine accelerates diabetes induced retinal changes

This study investigated the influence of nicotine in an experimentally induced diabetic rat model. They used non-invasive high-resolution spectral domain optical coherence tomography (SD-OCT) imaging to provide quantitative information on the temporal alterations of retinal structures at the micrometer resolution...

ABCA1 mediates lipid efflux in the retina

Age-related macular degeneration (AMD) is the leading cause of blindness in the elderly population. There are two forms of AMD, dry and wet, the latter so named because of the presence of choroidal neovascularisation. Both forms lead to retinal pigment...

Postoperative astigmatism

The authors investigate the short and long-term postoperative refractive effects of medial rectus recession on the involved eye and explain the detectable effects in detail by the results of vector analysis in 52 eyes and 32 patients. The subjects had...

Ocular blood flow changes in Behcet disease

This study evaluates ocular blood flow changes in both ocular Behcets disease (BD) and non-ocular BD (with or without thrombotic disease) and compares these findings with a healthy control group. A total of 90 eyes with BD were evaluated with...

Latanoprost in the treatment of congenital glaucoma

The aim of this study was to investigate the glaucoma control of latanoprost therapy in primary congenital glaucoma (PCG) and assess the factors affecting long-term outcome. Eighty-one eyes of 44 patients with PCG and 42 eyes of 29 patients with...

Impact of orthoptic re-exam in screening

The authors evaluated whether the re-examination within the orthotic screening in children with questionable results at the first examination can reduce the number of submissions to specialists and avoid a high number of false positives. This was a retrospective study...

Clinical features and mortality of endogenous panophthalmitis in China

This longitudinal cohort study aimed to report the clinical features, treatment strategy, and mortality of 15 consecutive patients (16 eyes) with endogenous panophthalmitis (EP) at a tertiary medical centre of the largest eye centre in Northern China. Mean age was...

Impact of COVID-19 on orthoptic services during a recovery phase

The purpose of this study was to conduct a follow-up survey of orthoptic practice in the UK and Ireland during the summer 2020 interim recovery phase of the pandemic. This was a prospective cross-sectional survey from July 1 2020 to...

Changes in C:D ratio of premature infants with enlarged C:D ratios

This retrospective observational study examined the longitudinal alterations in cup to disc ratio (CDR) among premature infants exhibiting enlarged CDR and normal intraocular pressure (IOP) up to two years. Among the 283 infants, 13.4% manifested an enlarged CDR. In this...