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New mouse model of diabetes mellitus

Diabetic retinopathy (DR) is a serious complication of diabetes. It is driven by the loss of pericytes, cells which control vascular function, due to excess formation of sugar alcohols by the enzyme aldose reductase (AR). AR has been shown to...

Wet AMD outcomes post cataract surgery

The authors present the findings of a retrospective study looking at the progression of wet age-related macular degeneration (AMD) in patients who underwent cataract surgery. They recruited a series of 111 patients of which 38 were men and 73 were...

Oral Ibuprofen reduces early bleb failure in high risk trabeculectomy

In this retrospective cohort study, 288 eyes of 273 patients (mean ±SD age: 68.56 ±10.47 y; 32.60% females) with primary glaucoma who underwent trabeculectomy / phacotrabeculectomy at the Singapore National Eye Centre between April 2020 and April 2021 with a...

Blind Inverclyde woman finds her voice

Claire Forde (29) from Greenock is no stranger to a microphone. Her journey into public speaking took a major step forward this year when she joined a newly launched Speakers Club, created to improve the confidence and communication skills of...

What can we learn from Jimmy McGill?

A few months ago, my eldest son got me interested in a Netflix series called “Better Call Saul”. This is a spin-off from another series called “Breaking Bad”, although I confess to not having seen any of those episodes as...

Meltdown, Spectre, Flying Hospitals and Spy Cams

iPhone slowdown In early 2018 users discovered that Apple was slowing down older iPhones intentionally. The reported reason was to prolong the usable battery life. These changes were made without the knowledge or consent of owners. Unsurprisingly, a community backlash...

CALL TO ACTION: Ophthalmology on Myanmar / Thailand border: do you have any redundant kit?

In 1990, the late Doctor Frank Green, a consultant ophthalmologist in Aberdeen, along with Doctor Phillip Ambler, a GP with ophthalmic training, responded to an invitation to provide ophthalmic care for Karen refugees on the northern and eastern Myanmar borders....

Strengthening the signal: Advancing oculomics research for systemic health insights

Oculomics, the study of how ocular structure reflects systemic health, is poised to become an integral tool for predicting, triaging, and diagnosing a wide range of diseases. By analysing data from the eye, particularly the retina, healthcare providers can gain...

Large language models in ophthalmology

Traditional artificial intelligence (AI) models typically require large amounts of labelled data for training. For example, to develop a model capable of detecting macular pathologies on optical coherence tomography scans, thousands of scans would need to be manually labelled by...

The 2020 Milgram Experiment

Will ophthalmology recover from COVID-19? Learning Curve columnist Gwyn Samuel Williams shares his thoughts on the developing impact of the pandemic “It’s busy today,” the nurse in green chuckles. “There are six patients I think.” Six. This clinic is designed...

My COVID-19 songs

A portrait of Anna by Tamara Jovandic-Everson as part of #portraitsforNHSheroes. I am a consultant eye surgeon and these are my COVID songs. First of all, I have not even had time to digest the past six months, partly because...

In conversation with Robert Henderson

Revolutionary eye treatments offer hope for children facing blindness from CLN2 batten disease. Robert Henderson discusses this, and his use of Heidelberg Engineering’s Spectralis device to better combat it. Pioneering research from Great Ormond Street Hospital (GOSH) and the University...