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Optical coherence tomography in patients exposed to vigabatrin
Vigabatrin is used to treat epilepsy and can lead to increased levels of gamma-aminobutyric acid (GABA) in the brain and in the retina leading to binasal visual field defects. Although not the first line of treatment for adults it is...
Sclerotomy suturing
This was a retrospective review of 589 consecutive cases of patients who underwent 23-gauge tranconjunctival pars plana vitrectomy. Cases were split into Type 1 vitrectomies (macular hole, ERM and simple vitreous haemorrhages) and Type 2 cases which were more complex...
Using frequency doubling technology perimetry to identify Alzheimer’s disease early
Alzheimer’s disease is widely reported to be associated with deficits in visual function. Visual disturbances include impaired stereopsis, contrast sensitivity and motion detection. Deficits specific to the magnocellular pathway (MGC) have been identified in Alzheimer’s disease. This article compares the...
Antibiotic prophylaxis after intravitreal injections
The use of topical antibiotics as prophylaxis after intravitreal injections is a contentious issue, especially now with increasing use of intravitreal anti-VEGF agents. In the Wills Eye Institute, prior to May 2011, all patients undergoing intravitreal injections in the office...
Evaluation of keratometry with a novel colour LED corneal topographer
The Cassini topographer (i-Optics), which analyses corneal shape based on the reconstruction of specular reflections on 679 coloured LEDs, generates keratometry and is the new machine being compared in this study with other keratometry devices. The prospective comparative study included...
Swept-source OCT for measuring peripheral anterior synechiae
The authors report on a cross-sectional study looking at swept-source optical coherence tomography (SS-OCT) for measuring the area and degree of peripheral anterior synechiae (PAS) in patients with angle closure glaucoma. The SS-OCT is commercially available, has a laser wavelength...
Combined PRK and CXL in keratoconus
This study aimed to investigate the results after photorefractive keratectomy (PRK) followed immediately by standard 30-minute corneal cross-linking (CXL) for keratoconus. This retrospective study included 26 eyes of 16 patients with keratoconus. Uncorrected distance visual acuity (UDVA), corrected distance visual...
Review of pathogenesis of Acanthamoeba keratitis
In this review, the author summarised the current microbiomic and immunological evidence related to the pathogenesis of Acanthamoeba keratitis (AK). AK has been described for almost 50 years, but the exact biology of the disease remains perplexing. Acanthamoeba spp. are...
Fifteen-year results of phakic artisan IOL for hyperopia correction
This retrospective review of a cohort of 61 eyes from 32 patients offers long-term results for phakic Artisan (Ophtec BV) iris-fixated phakic IOL (IF-pIOL). The mean age at surgery was 41.6 years with a range of 25-59 years. Refractive outcomes...
Prevalence and risk factors for ROP in Saudi Arabia
This study aimed to establish the prevalence of retinopathy of prematurity (ROP) among high-risk neonates in a tertiary centre, identify the most commonly associated risk factors and highlight the benefits of early treatment of type 2 ROP and ROP milder...
Can coenzyme Q10 have a protective role in ethambutol-induced retinal ganglion cell toxicity
Tuberculosis (TB) is one of the most prevalent infectious diseases, especially in developing or low- income countries. Ethambutol is a widely used drug to treat TB. Ethambutol can cause visual disturbance including ethambutol toxic optic neuropathy (ETON). ETON is one...
