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Leber’s hereditary optic neuropathy: from lab to clinic

Leber’s hereditary optic neuropathy (LHON) was the first clinically described mitochondrial disorder (1871). This article reviews the pathophysiology and clinical features of LHON with a focus on translational research. G11778A is currently the most common mutation worldwide and is associated...

AI can identify treatment gaps for patients with macular disease, study shows

Using artificial intelligence (AI) in eye clinics could reduce both undertreatment and overtreatment of neovascular or ‘wet’ age-related macular degeneration (AMD). AMD is the leading cause of irreversible vision loss in older people and accounts for around 1 in 10...

International Ocular Inflammation Society (IOIS) Congress September 2023 in a sweltering Berlin

Approaching its 40th year, IOIS remains focused on advancing research and knowledge-sharing around ocular inflammatory diseases.

Effects of phacoemulsification on IOP and drug use in glaucoma

For patients with comorbid cataract and primary open-angle glaucoma (POAG), guidance is lacking as to whether cataract extraction and traditional filtering surgery should be performed as a staged or combined procedure. Achieving this guidance requires an evidence-based understanding of the...

Intraoperative floppy iris syndrome and prevalence of intraoperative complications

Alpha-blockers (particularly of the selective type) are known to be associated with intraoperative floppy iris (IFIS) and poor dilation, which can present in various severities during cataract surgery and need to be recognised in order to avoid intraoperative complications. Methods...

MRI characteristics of NMO, MOG and MS-related ON

This review article examined differences of MRI appearances that can help clinicians assess and manage these important neuro-ophthalmic disorders. It also examined the role of optic nerve MRI as a prognostic indicator in acute optic neuritis (ON). The major findings...

Evaluation of Optive® in ocular discomfort after anti-VEGF intravitreal injection

In this study the authors prospectively evaluated the efficacy of Optive® eye drops after in full, then abbreviation - intravitreal injection (IVT). Patients naïve to IVT were included in the study. No artificial tear treatment was prescribed after the first...

Does the length of the school day have a role in age of myopia onset?

The authors prospectively collected the refractive data of myopic adults attending recruiting dispensing optician or ophthalmologist sites. Participants were recruited consecutively, giving verbal informed consent. Sites included a mix of urban and rural areas across eight sites. The following data...

Chandelier-assisted versus standard scleral buckling for rhegmatogenous retinal detachment repair. Systematic review and meta-analysis

Despite a significant global decline in standard scleral buckling (SSB) procedures for rhegmatogenous retinal detachment (RRD), it continues to hold its place as an essential treatment option, offering distinct advantages such as cost-effectiveness, preservation of the vitreous, improved final visual...

Vabysmo receives NICE approval

The National Institute for Health and Care Excellence (NICE) has recently approved Vabysmo▼(faricimab) for treating adults with visual impairment due to macular oedema secondary to branch and central retinal vein occlusion (BRVO and CRVO). The NICE approval of Vabysmo was...

Advancing Eyecare (AEC) acquires Birmingham Optical Group

Advancing Eyecare (AEC), a leading North American provider of ophthalmic instruments, has acquired Birmingham Optical Group, a top UK supplier of optical equipment and services. The terms of the deal were not disclosed. With over 60 years of industry experience,...

The role of artificial intelligence in cataract surgery: An overview

Cataracts are still a leading cause of blindness and, with an ageing population, that burden will only grow [1]. Increasingly experts are leaning on technology such as ‘Surgery 4.0’ [2] – where smart machines and artificial intelligence (AI) slide into...