You searched for "metastatic"
Insights from the ‘Rb-NET Challenges’ Session: Evolving approaches in global retinoblastoma management
2 April 2025
| Mattan Arazi, Ido Didi Fabian, Nick Astbury, Brenda Gallie (Prof), Covadonga Bascaran, Marcia Zondervan
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EYE - Paediatrics, EYE - Pathology, EYE - Oncology
The Retinoblastoma Network (Rb-NET) Multidisciplinary Team (MDT) platform, developed by the London School of Hygiene & Tropical Medicine (LSHTM) and Professor Ido Didi Fabian, is a web-based telemedicine initiative that regularly hosts virtual MDT meetings focused on the evaluation and...
Cavernous sinus syndrome
Anatomically the cavernous sinus is a plexus of multiple veins that are connected and within this plexus there are several important vascular and neurological structures. These include cranial nerves III, IV, V1 (and sometimes V2), VI as well as the...Ciliary body granuloma masquerading as a melanoma
3 February 2023
| Boon Lin Teh, Paul Cauchi, Lucia Kuffová
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EYE - General
Introduction Sarcoidosis is a multisystem granulomatous inflammatory condition which predominantly affects the pulmonary system and intrathoracic lymph nodes, followed by ocular involvement [1]. We present an interesting patient who developed acute anterior uveitis and subsequent ciliary body granuloma clinically mimicking...
Corneal stroma modelling under hypoxic conditions
1 August 2018
| Graham Wallace
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EYE - Cornea, EYE - General
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Confocal fluorescence microscopy, Cornea, Corneal organ culture, Extracellular matrix, Stroma
The cornea is exposed to hypoxia under several conditions including sleep, inflammation and wound healing. Being an avascular tissue to maintain transparency, how the cornea homeostatic controls oxygen tension is important. To address this process two models were utilised; a...
Glaucoma medications and ocular surface disease
3 August 2023
| Su Young
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EYE - Glaucoma
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Drug allergy, OSD, drug toxicity, drug-induced cicatricial keratitis, dry eye, glaucoma medications, ocular surface disease
This literature review examined ocular surface disease (OSD) associated with glaucoma medication. The authors examined the prevalence of features and management guidelines glaucoma medication associated OSD. Fifty-eight articles published within the past five years are included in this review and...
Periocular sweat gland carcinomas
This is an interesting review of a rare group of tumours which together comprise the adnexal sweat gland carcinomas. Although there are only 22 patients, this is the largest cohort ever published. The authors summarise the clinical presentation, stage, management...
Results of changed treatment for retinoblastoma
Systemic chemotherapy was adopted in Kobe in 1996. In this study the authors analyse the clinical manifestations and results of treatment for patients with retinoblastoma since then. This review is of 43 eyes of 34 patients. Those with follow-up to...
Diagnosis and management of solitary fibrous tumour
This is a retrospective review of 21 patients diagnosed with solitary fibrous tumour of the orbit between 1996 and 2018 at a single centre. The authors reviewed the clinical presentation, management and course of the disease and reanalysed the histopathology...
Differentiating orbital tumours on MRI
This is a literature review examining the ability of specific MRI modalities to differentiate between benign and malignant tumours of the orbit. The authors identified 29 articles reporting diffusion weighted image (DWI) values and corresponding apparent diffusion coefficients (ADC) for...An eye on novel anti-cancer agents: an evidence-based approach to external eye assessment
Novel anti-cancer therapies have led to significant advancement in cancer treatment, however, they can be associated with external eye complications. It is important to be mindful of such adverse effects during assessment of patients enrolled in clinical trials. Annually, approximately...
Biopsy of nasolacrimal duct using sheath guided dacryoendoscopy
1 August 2019
| Rina Bhatt
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EYE - Neuro-ophthalmology
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Dacryoendoscopy, biopsy, immunohistochemistry, nasolacrimal duct obstruction, sheath-guided endoscopic probing (SEP)
In this study the author’s biopsied six eyes of five individuals with recurrent nasolacrimal duct obstruction following a prior dacryoendoscopic probing. All procedures were performed under local anaesthetic, the obstruction or lesion was directly visualised with dacryoendoscope and biopsy was...
Endophthalmitis after intravitreal anti-VEGF injection
1 August 2019
| Sofia Rokerya
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EYE - Vitreo-Retinal
The authors report the results of a retrospective multicentre study conducted at 17 retina referral centres to investigate the microbial spectrum of endophthalmitis after anti-VEGF injections. A total of 83 cases of culture-positive endophthalmitis (58.4%) were included. The most frequent...
