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Expert vs. non expert grading of ROP from digital video images

The primary purpose of this study was to determine whether digital video images of the retina obtained using an indirect ophthalmoscope imaging system could be accurately graded for zone and stage of retinopathy of prematurity (ROP) and the presence of...

Intensive diabetes therapy and ocular surgery in type 1 diabetes

The Diabetes Control and Complications Trial (DCCT) ran between 1983 and 1993 and showed that intensive glycaemic control was beneficial in reducing diabetic retinopathy in type 1 patients. There was a 76% reduction in onset of retinopathy and a 52%...

Long-term effect of gene therapy on Leber’s congenital amaurosis

After reporting the first successful gene therapy results for RPE65 deficiency in three patients in a brief report in 2008, the same team from London now report the results of 12 patients followed up for three years after transfection. As...

Association between serum triglycerides and pan retinal photocoagulation in type 1 diabetes

This retrospective cohort study aimed to examine whether dyslipidaemia is a risk factor for progressing to proliferative diabetic retinopathy (PDR) and consequently requiring pan retinal photocoagulation (PRP) treatment in type 1 diabetics. In previous studies including the ETDRS study an...

Cytokine levels in vitreous fluid in patients with pathological myopia

Pathological myopia (PM) is a leading cause of irreversible visual impairment worldwide, and efforts are dedicated to the study of its underlying mechanisms. Axial extension of the eyeball is regulated via a cascade of biochemical molecules that are initiated in...

Does religious fasting affect intraocular pressure or retinal parameters?

Nearly one billion Muslims fast every year during the month of Ramadan. Due to the difference between the lunar and solar calendars, religious fasting time can range from 11 to 17 hours per day. This prolonged abstinence from food and...

A scoping review of artificial intelligence tools for diabetic retinopathy in low- and middle-income countries

The authors conducted a scoping review to summarise the literature relating to artificial intelligence (AI) tools for diabetic retinopathy (DR) in low- and middle-income countries (LMICs). Eighty-one studies were included, following a comprehensive literature search. The majority of studies were...

Epidemiology of ocular cancer in Cali

The aim of this study was to describe the population trends of incidence and survival rates of ocular cancer in Cali, Columbia. Data was retrieved from the Registro Poblacion de Cancer de Cali (RPCC, i.e. Population Cancer Registry of Cali)...

Normative data using a virtual reality game-based visual field test

The authors present a prospective cross-sectional study involving healthy children to assess the use of a virtual reality game-based perimetry assessment. A single eye centre recruited through paediatric optometry and ophthalmology clinics over a 12-month period. Children aged <18 years...

Retinoblastoma management update (part 1): clinical features, diagnosis and genetics

The first of a two part series, this article will discuss the clinical features, diagnosis and genetic aspects of retinoblastoma. Manoj Parulekar is based at Birmingham Children’s Hospital, one of the two designated national retinoblastoma and paediatric ocular oncology treatment...

Interspecialty referrals

Referrals between the many and varied branches of ophthalmology sometimes underline how sub-specialised we have all become nowadays. The old era when everyone was an ophthalmic jack of all trades is gone, for better or for worse, and instead of...

What's trending Aug/Sept 2019

#puppydogeyes Who can resist a pair of puppy dog eyes? It may be that no human can! A team of researchers discovered that dogs acquired a new forehead muscle, which is scanty or absent in wolves. This muscle is the...