You searched for "impaired"
Associations between cerebral vascular malformations and retinal venous malformations
The authors present a retrospective medical notes review which aimed to understand associations between retinal venous malformations (RVM) and cerebral vascular malformations (CVM). Cases of known CVM over a four-year period were identified. The data extracted from medical records included...
Understanding optic nerve head pericytes and glaucoma
The authors provide a comprehensive review of the current understanding of pericytes in the optic nerve head (ONH). Key points include: (1) Pericytes are contractile mural cells that play crucial roles in regulating blood flow, maintaining the blood-brain / blood-retinal...
AI glaucoma screening cost-effective in the Netherlands?
Population-wide screening for glaucoma has traditionally been deemed not cost-effective due to high costs and low disease prevalence. This Dutch study re-evaluates this position by introducing artificial intelligence (AI) to the screening model. The authors developed a health-economic model comparing...
Topical cyclosporine A 0.05% for recurrent anterior uveitis
This is a retrospective case-crossover study conducted by reviewing medical charts of patients treated for recurrent anterior uveitis between 2002 and 2011 at the Kellogg Eye Centre by one cornea specialist. The demographics, episodes of anterior uveitis, severity of episodes...
Comparison of SS-OCT and SD-OCT in polypoidal choroidal vasculopathy
Swept source OCT (SS-OCT) is known to have a longer wavelength than spectral domain OCT (SD-OCT), allowing deeper penetration into retinal and choroidal layers. The aim of this study was to investigate whether SS-OCT is superior to SD-OCT in imaging...
Adjuvant oral voriconazole or oral ketoconazole for fungal keratitis
This randomised double-blinded trial examined clinical outcomes of 50 patients with severe fungal keratitis treated with either adjuvant oral voriconazole or oral ketoconazole. Inclusion criteria were culture or smear proven fungal ulcers >5mm in maximum diameter, involving >4mm of the...
Effect of anti-VEGF treatment on PED morphology
This retrospective study of 30 eyes assessed the effect of anti-VEGF on morphology of pigment epithelial detachments (PED) secondary to age-related macular degeneration (AMD). Thirty eyes of 28 patients with PED were compared to 30 eyes of 30 patients with...
A randomised, controlled trial of oral propranolol in infantile haemangioma
Since its use was first reported in the New England Journal in 2008, propranolol has become the preferred treatment for infantile haemangiomas. However, there is no consensus as to the optimum dose or duration of treatment and there is a...
Comparison of ganglion cell thinning in glaucoma vs. macular hole repair
This prospective study compared the changes in the photopic negative response of the focal macular electroretinogram (fmERG) caused by retinal ganglion cell complex (GCC) thinning at the macula between patients with open angle glaucoma (OAG) and 12 months after successful...
Evaluation of keratometry with a novel colour LED corneal topographer
The Cassini topographer (i-Optics), which analyses corneal shape based on the reconstruction of specular reflections on 679 coloured LEDs, generates keratometry and is the new machine being compared in this study with other keratometry devices. The prospective comparative study included...
Mitomycin C versus 5-FU as an adjunctive treatment for trabeculectomy
Antifibrotic agents are used during trabeculectomy (TRAB) to improve long-term surgical success by reducing fibrosis of subconjunctival and episcleral tissue. The purpose of this meta-analysis was to directly compare the efficacy and safety of the two most frequently used antifibrotic...
