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Exploiting nature’s randomised trials of eye disease

Confounding and reverse causation in observational ophthalmic epidemiology Traditional observational studies are inherently limited in establishing a causal effect of an exposure on an outcome of interest. One fundamental limitation is confounding, whereby causation is incorrectly attributed to a third...

Systemic sarcoidosis presenting with acute myopia and angle closure

Case report A 40-year-old Asian man presented to the Emergency Department with a one day history of sudden onset visual disturbance in his right eye. He complained of image distortion and noted that objects now appeared smaller. He also described...

Photophobia: an unusual symptom of a pituitary macroadenoma

Introduction Photophobia, defined as ‘an abnormal intolerance to light’, is commonly associated with a range of both ocular and neurological pathologies such as dry eye, blepharospasm, corneal pathologies, cataracts, uveitis, retinal dystrophies, optic neuritis, migraine, meningitis, and traumatic brain injury...

25 years of OCT

David Huang first described optical coherence tomography (OCT) in 1991, in his seminal paper on the subject in Science. This method developed the work of others on ophthalmic interferometry, which essentially showed that measuring reflected light could be used to...

Specialist high-street eye clinics for managing patients with retinal disorders can enhance care standards

The author examines the successful introduction of community-based retinal clinic services by Manchester University NHS Foundation Trust. Dr Sajjad Mahmood, Consultant Ophthalmologist, MREH, shares experience of establishing community-based medical retina clinic services. Sight loss from age-related macular degeneration (AMD), cataract,...

Comparison of bilateral lateral and unilateral recession resection for IXT

This is a retrospective review study of patients between the ages of three and 15 years old with the basic type of intermittent exotropia (IXT) who had strabismus surgery between January 2003 to September 2009. There were 85 patients included...

Scleral fixation using Gore-Tex suture of a subluxated PCIOL

This was a retrospective single-centre study of patients who underwent lasso in-the-bag scleral fixation of a subluxated posterior chamber (PC) intraocular lens (IOL) using the snare technique with Gore-Tex suture from 2019 to 2021. Functional outcome was analysed by clinical...

Tutopatch® in surgical management of third nerve palsy

his study evaluates the benefit of using Tutopatch® to elongate the extraocular muscles in patients with third nerve palsy who have residual strabismus after unsuccessful surgery and no other surgical options considered to be appropriate. The study included nine patients...

Orbis celebrates International Day of Friendship

International eyecare charity Orbis recognises the importance of strong bonds on International Day of Friendship 2023.

Trabeculectomy for normal tension glaucoma

This is a retrospective consecutive, non-comparative case series of 131 eyes of 98 patients undergoing trabeculectomy between 2007 and 2013 in a normal tension glaucoma (NTG) clinic. Assessment of the clinical outcomes include intraocular pressures (IOP) reduction, bleb formation, final...

Endophthalmitis after intravitreal injections in France

In this nationwide, retrospective, multicentre case series, the authors looked at the incidence and characteristics of endophthalmitis after intravitreal injections of anti-VEGFs and steroids, given for a variety of posterior segment conditions (macular oedema secondary to diabetes or retinal vein...

Intravitreal ranibizumab for the treatment of myopic CNV

The authors conducted a prospective study. Sixty-four patients (65 eyes) attended the 12-month follow-up examination. The mean patient age was 47.8 years. Fifty-five patients (86.0%) were females. All patients had pathologic myopia (a spherical equivalent of more than − 6.0...