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Preventing blindness from diabetes: planning a programme of service development and research across Malawi

In sub-Saharan Africa 19.4 million people have diabetes; this is projected to rise to 28.6 million by 2030 [1]. Sight loss from diabetes devastates the lives of working people, affecting the financial stability of the families and communities who depend...

Stem cell therapy for Parkinson’s disease: researching for an 
effective cure

Neurodegenerative diseases are characterised by the chronic and progressive loss of neurons, which in turn results in loss of cognitive and physical functions. The World Health Organization has estimated that the disability-adjusted life years lost from neurological disease was about...

Practice tips: Directions in cataract surgery services and preventing postcataract endophthalmitis

Future directions in the delivery of high quality cataract surgery services and approved intracameral prophylactic approaches to lowering the risk of postcataract infective endophthalmitis were debated by consultant ophthalmic surgeons in a recent London seminar, held at the Royal Society...

Simulating the visual impairment symptoms of age-related macular degeneration in virtual reality

A new virtual reality application visually simulates age-related macular degeneration and demonstrates its progression over time including some Charles Bonnet syndrome hallucinations. Introduction Age-related macular degeneration (AMD) is the leading cause of blindness in developed countries with the prevalence of...

Move 78

The Soviet Union still existed throughout my formative years, along with a vague undefinable miasma of possible war that generated films such as Red Dawn and Rocky IV. My favourite film from that era was called War Games, in which,...

Conference Report: ARVO 2025 Annual Meeting

The Association for Research in Vision and Ophthalmology (ARVO) 2025 Annual Meeting was held at the Salt Palace Convention Centre in Salt Lake City, US. This prestigious event brought together experts in vision and ophthalmology from around the world for...

Kabgayi International Ophthalmology Conference 2024

by Michael Mikhail, FRCOphth, Consultant Ophthalmologist; Vitreoretinal Surgeon, Kabgayi Eye Unit, Rwanda. My journey to Rwanda in April 2022 aimed to expand vitreoretinal services, but it also highlighted the need for robust scientific discourse, akin to the UK's ophthalmology culture,...

Achieving post-op target range increases success of strabismus surgery in adults

This is a retrospective cohort study of all patients over 12-years old undergoing strabismus surgery under a single surgeon in a tertiary referral centre in Toronto, Canada. The aim of the study is to determine the role of achieving immediate...

Aflibercept treatment in polypoidal choroidal vasculopathy

The authors present a study to evaluate the anatomical and functional efficacy of aflibercept intravitreal (IVT) as a monotherapy in polypoidal choroidal vasculopathy (PCV) in a Caucasian population treated with initial three-monthly aflibercept IVT, followed by a bimonthly regimen for...

Transient thickening of the macular retinal nerve fibre layer in acute optic neuritis

Acute optic neuritis (ON) causes axonal degeneration, which can be quantified from the blood by neurofilament protein (Nf) levels. Within about three months, atrophy of the retinal nerve fibre layer (RNFL) follows. However, it remains challenging to explain why there...

Patterns of binocular diplopia in giant cell arteritis (GCA)

Giant cell arteritis (GCA) is a granulomatous vasculitis that targets medium and large sized vessels. Binocular diplopia has been reported in a small number of patients with visual manifestations of GCA. It can be caused by ischaemia in any segment...

Intravitreal dexamethasone in diabetic macular oedema (DMO) - enhancing the response to anti-VEGF in non- or poor responders

This study aimed to describe the outcomes of a switch back from DEXi (dexamethasone implant) to anti-VEGF therapy in eyes that were treated temporarily with DEXi after an initial poor response to anti VEGF. Twenty-three eyes of 17 patients were...