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Ophthalmic Genetics cover picture

Microvascular disease in Alport syndrome

2 December 2019 | | EYE - Paediatrics, EYE - Strabismus
The authors present the findings of a retrospective case-control observational study on increased microvascular disease in individuals with Alport syndrome recruited over a 21-year period. They recruited 28 males and 28 females with X-linked Alport syndrome (XLAS) and eight men...

Near-infrared autofluorescence to diagnose retinal laser injuries

2 December 2019 | | EYE - Vitreo-Retinal
This retrospective observational case series aimed to assess whether near infrared autofluorescence (NIR-AR) imaging is a useful imaging modality in the diagnosis of hand-held laser retinal injuries. Twelve patients from two centres underwent ophthalmic assessment and retinal imaging including fundus...
Journal of Pediatric Ophthalmology & Strabismus cover image.

Significant associations to presence of significant retinal haemorrhages in suspected child abuse

1 September 2023 | | EYE - Paediatrics, EYE - Strabismus
The authors aimed to extract statistically significant associations between non-ocular clinical and diagnostic imaging findings and the presence of significant retinal haemorrhages, and then develop an evidence-based screening algorithm to determine when to consult an ophthalmologist in suspected child abuse...
Ophthalmic Genetics cover picture

Patient reported outcomes in adolescents with inherited retinal diseases

4 October 2023 | | EYE - Vitreo-Retinal | PROM, Patient-reported outcomes, clinical trial, gene therapy, inherited retinal disease, pediatrics, retinal dystrophy
This was a two-centre validation study of two sets of patient reported outcome measures (PROMS) for adolescents (13-17- years-old) with inherited retinal diseases. The measures were the Michigan Retinal Degeneration Questionnaire (MRDQ) and the Michigan Vision-Related Anxiety Questionnaire (MVAQ). Both...

Early structural and functional retinal changes in intermittent exotropia

28 February 2025 | | EYE - Paediatrics
This study aimed to evaluate and compare spectral domain optical coherence tomography (SD OCT) and electrophysiological measures in patients with intermittent exotropia and healthy controls, to outline changes in retinal and optic nerve structure and function. This was a cross-sectional...

AI breakthrough brings geographic atrophy treatment a step closer

20 September 2021
A team led by Dr Konstantinos Balaskas at Moorfields Eye Hospital Reading Centre has developed a fully automated, deep-learning model (algorithm) that can detect and quantify geographic atrophy using standard optical coherence tomography (OCT) scans.

Rite of passage

1 February 2016 | | EYE - Cataract, EYE - Cornea, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal, EYE - General
The Lakota Sioux people of Dakota have one of the best preserved Native American cultures in the United States and when people think of the ‘American Indian’ it is to the culture of the Lakota Sioux that people mostly turn....

Choosing a subspecialty

1 October 2019 | | EYE - Cataract, EYE - Cornea, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal, EYE - General
It is quite worrying how many registrars reach the final years of training without choosing a subspecialty. Sometimes this is because they love everything and cannot countenance giving any of it up, but more commonly this is due to various...

The writing on the wall

1 December 2021 | | EYE - Cataract, EYE - Cornea, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal, EYE - General
The Prophet Daniel tells a famous tale of how the tyrannical king of Babylon held a feast for all his top lords and ladies, and as the feasting grew to fever pitch a mysterious hand appeared from nowhere that started...

Feb/Mar 2016 Quiz 2

1 February 2016 | | EYE - Cataract, EYE - Cornea, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal, EYE - General
History A 30-year-old male presents with a phthisical left eye and undergoes enucleation. He has some lesions in his right eye that are under ophthalmic surveillance. Figure 1 is a low power of the enucleation. Figures 2, 3 and 4...

Managing a dislocated intraocular lens

1 October 2014 | | EYE - Cataract, EYE - Refractive
A 70-year-old male patient is referred from the optician with a history of onset of double vision and examination shows a dislocated / subluxated IOL. How will you manage this patient? If the double vision is causing serious concern to...

A case of late spontaneous subluxation of in-the-bag intraocular implant

1 April 2017 | | EYE - Cataract, EYE - Refractive
An 82-year-old frail lady was referred by her optometrist with a finding of subluxated implant in the right eye. She had uneventful phacoemulcification with in-the-bag intraocular implant 17 years earlier. There is no history of having had pseudoexfoliation (PXF) or...