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My Top Five: Promising gene therapies for ocular conditions

4 December 2024 | | EYE - Vitreo-Retinal
Gene therapy, a pivotal advancement in modern medicine, particularly shines in ophthalmology. By targeting defective genes with engineered vectors, this approach promises significant strides in treating inherited retinal diseases. This article reviews the top five gene therapies in late-stage trials,...

My Top Five: Innovations in the diagnosis of ocular tumours

4 February 2025 | | EYE - Oncology, EYE - Orbit, EYE - Pathology
Ocular tumours can vary widely in origin, from benign growths to metastases from distant disseminated malignancies. Although rare, ocular tumours pose a significant health and economic burden globally, with ocular cancers accounting for 0.2% of all diagnosed malignancies in the...

The ghost of Christmas present

1 December 2022 | | EYE - General
“Ah, youth is wasted on the wrong people.” Some will recognise this as one of the many brilliant quotes from what is considered to be the best Christmas movie ever – Frank Capra’s tear-jerker It’s a Wonderful Life (1946), although...

Coaching: Supporting doctors’ development and wellbeing

20 October 2025 | | EYE - General
Supporting and retaining the workforce is a top priority for all NHS organisations, but it’s not clear how best to do this, or how such support should be funded. Junior doctors have clinical and educational supervision, and the quality of...

Congenital cataract

4 December 2025 | | EYE - Cataract, EYE - Paediatrics
Congenital cataract is the clouding or opacification of the lens that occurs at birth or weeks after (infantile cataract). They can be unilateral or bilateral and vary in form, size and location, and consequently the visual impact, management course and...

Tricks and tips for paediatric refraction

4 December 2025 | | EYE - Paediatrics
Refraction is an important part of the paediatric eye examination but can sometimes be challenging. If a child struggles to co-operate with the eye examination, how can one ensure that the best outcome is achieved? There are tips here which...

The management of retinal vein occlusions: a summary

1 February 2015 | | EYE - Cataract, EYE - Refractive, EYE - Cornea, EYE - Imaging, EYE - Vitreo-Retinal, EYE - General
Retinal vein occlusions (RVO) are the most common cause of visual loss from retinal vascular disease second to diabetic retinopathy. Vision is lost due to ischaemia, macular oedema and / or haemorrhage which ultimately effects a patient’s quality of life...

Retinopathy of prematurity treatment in the South West of England: long-term outcomes 1997-2008

1 December 2014 | | EYE - Vitreo-Retinal
Retinopathy of prematurity (ROP) is a condition that affects the developing retinal vascular system of pre-term babies. If left untreated, ROP can lead to severe visual impairment. The severe visual impairment caused by untreated ROP can be prevented by screening...

A look into the IOL space

1 October 2014 | | EYE - Cataract, EYE - Refractive
Advances in the design and performance of intraocular lenses (IOLs) continue to be driven by demand for better outcomes, presbyopia correction and spectacle independence, alongside a better understanding of the dynamics of the crystalline lens, newer theories of accommodation and...

Quality matters in the management of serious eye disorders

1 June 2019 | | EYE - Cataract, EYE - Glaucoma, EYE - Neuro-ophthalmology, EYE - Vitreo-Retinal
The author discusses the first quality standard for serious eye disorders from NICE and takes a look at new care models for enhanced service delivery. Patient backlogs pose risks to patient safety, with research showing that people are losing sight...

Treating minor eye conditions in optometry practices: is this a viable model for the future?

1 June 2018 | | EYE - General
The role of the optometrist has expanded in recent years as community eye care services have changed. With the limited scope of general ophthalmic services (GOS) regulations in most parts of the UK, the funding to support additional care has...

Strabismus in thyroid eye disease

1 April 2017 | | EYE - Paediatrics, EYE - Strabismus
Pathogenesis Thyroid eye disease (TED) is an auto-immune condition, in the initial phase there is lymphocytic infiltration and oedema of the extraocular muscles with deposition of glycosaminoglycans and hyaluronic acid and adipogenesis, which can lead to an increase in the...