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Pathophysiology of diabetic macular oedema: why combination therapy may be better
The prevalence of diabetes has continued to increase over the years. It is currently estimated that there are 382 million with diabetes worldwide in 2013, and that this figure is expected to rise to 592 million by 2035 [1]. In...
How to achieve 1% solution of Lissamine green
Lissamine green (LG) concentration of 1% is clinically effective in the diagnosis of ocular surface disease. LG is now commercially available only in a form of dye-impregnated strips, whose concentration is insufficient. This study examined how to achieve 1% concentration...
Conjunctival inflammation in glaucoma patients
Numerous studies have demonstrated that topical medications and preservatives used for the management of glaucoma can induce significant histopathologic and inflammatory changes in the ocular surface. This study describes an increased expression of major histocompatibility complex class II antigen HLA-DR,...
Chronic drop use and trabeculectomy on tear osmolarity
Ocular surface disease (OSD) is common in patients chronically treated for glaucoma. This may be related to the drug itself but often to the preservatives in the medication. Much work has been done on the most common preservative, benzalkonium chloride...
Nepafenac punctal plugs after cataract surgery: a new alternative?
The nepafenac punctal plug delivery system (N-PPDS) is an experimental L-shaped plug made of nonbiodegradable, preservative-free medical-grade silicone. It can deliver a sustained level of nepafenac for six weeks. This is a prospective, randomised, parallel-arm, double-masked, placebo-controlled, phase II pilot...
Amniotic membrane transplantation for SJS/TEN
This is a retrospective study of consecutive patients who underwent amniotic membrane transplantation (AMT) in the acute stage of Stevens-Johnson syndrome (SJS) / toxic epidermal necrolysis (TEN) from Toronto, Canada, between 2009 and 2018 and had more than three months...‘The Way Forward’ champions clinicians as architects of patient-centred service redesign
The demographic time bomb poses the dilemma of how more healthcare can be delivered to the UK’s ageing population without commensurate growth in resources. The Way Forward Project provides a robust resource for clinical centres to better identify and implement...Royal College of Surgeons of Edinburgh recruiting new board members and trainee representative for SSBs
The Surgical Specialty Boards (SSBs) are constituted within the internal governance structure of the College and exist primarily to support, advise and assist the College and its Council across the breadth of core College activities as they relate to specialty...What's trending Oct/Nov 2025
A round-up of the eye-related hot topics that have been trending on social media over the last few weeks. #AlienEarth #TheEye One of the best shows to recently start streaming is, in my opinion, Alien: Earth. The cosmic horror of...
FOUNDATIONS OF INTRAOCULAR MICROSURGERY – Principles for Elite Performance Volume 1: Systemic Challenges
Cataract surgery is the most commonly performed intraocular surgery performed in the UK. It takes years of meticulous practice and experience to master the surgery and become a safe and slick surgeon. As the saying goes, “forewarned is forearmed.” Anticipating...
Effects of phacoemulsification on IOP and drug use in glaucoma
For patients with comorbid cataract and primary open-angle glaucoma (POAG), guidance is lacking as to whether cataract extraction and traditional filtering surgery should be performed as a staged or combined procedure. Achieving this guidance requires an evidence-based understanding of the...
