You searched for "visual loss"
Adaptive optics imaging: resolving single cells in the living eye
1 June 2014
| Michel Michaelides (Prof), Adam Dubis
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EYE - Cornea
The human retina is unique in the central nervous system (CNS) in that it can be directly visualised non-invasively. Technological advances of several imaging modalities, including optical coherence tomography (OCT), multichannel scanning laser ophthalmoscopy (SLO) and fundus photography, have afforded...
Ophthalmology history and examination – a guide for medical students
15 February 2023
| Abiya Amna Ahmed, Shaan Rashid
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EYE - General
*First author Students have very little exposure to ophthalmology during their years at medical school. Teaching consists of a handful of lectures followed by a short placement in which students are expected to practise histories and examinations on patients with...
Identifying life-threatening uveal melanoma: A directed application of general-purpose AI
Uveal melanoma (UM) is a rare but aggressive eye cancer, affecting approximately six people per million annually [1]. Uveal melanoma arises in three locations: the choroid, ciliary body, and iris. As the most common primary intraocular malignancy in adults, UM...The Arclight: A ‘pocket’ ophthalmoscope to revitalise undergraduate teaching?
Ophthalmoscopy should be a core skill for every doctor and should be firmly embedded in the undergraduate curriculum similar to the unquestioned position of the stethoscope. The simplicity of the Arclight means it is easy to useand, importantly, to learn...Optical coherence tomography – reinventing the eye examination
It has been 25 years since Huang et al. presented the first optical coherence tomography (OCT) images in Science [1]. With vast improvements in OCT technology over the years, it is now possible to acquire high-resolution cross-sectional images of the...A guide to utilising your time efficiently to develop clinical and procedural skills as an aspiring ophthalmologist
4 February 2025
| Shaswath Ganapathi
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EYE - General
Ophthalmology often receives limited coverage in the undergraduate medical curriculum, and the availability of foundation programme jobs in this field is also restricted, reducing exposure to this field for aspiring ophthalmologists. Even if you’re not planning to specialise in ophthalmology,...
An update on inherited retinal disorders (part 1) – overview and assessment of inherited retinal disease
1 October 2016
| Michel Michaelides (Prof)
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EYE - Vitreo-Retinal
Part 2 of this topic can be found here Inherited Retinal Disease (IRD) is the leading cause of blindness certification in the working age population (age 16-64 years) in England and Wales and the second most common in childhood [1]....
Crystalline keratopathy in monoclonal gammopathy of undetermined significance
2 April 2025
| Kar Yen Phoong
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EYE - Cornea
Monoclonal gammopathies encompass a group of plasma cell disorders characterised by the excessive production of abnormal monoclonal immunoglobulins in the bloodstream [1]. This category includes multiple myeloma, monoclonal gammopathy of undetermined significance (MGUS), amyloidosis and other lymphoproliferative disorders. Monoclonal gammopathy...
Macular holes: A brief review
1 August 2017
| Sidath Wijetilleka, Roger McPherson
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EYE - Vitreo-Retinal
The classification of macular holes has been modernised by OCT findings. This is a brief review and encompasses the historical literature on macular holes. A macular hole is an anatomical discontinuation of the neurosensory retina at the centre of the...
White dot syndromes
1 September 2015
| Gwyn Samuel Williams
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EYE - Vitreo-Retinal
It is fair to say that trainees and consultants who are not medical retina specialists are a bit scared of the so called retinal ‘white dot syndromes’. It is easy to understand why this is the case, as almost every...
The future of multi-professional working in eye care
5 October 2020
| Nikolaos Tzoumas
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EYE - General
How the integration of service improvement technology, and health promotion will allow eye care professionals to overcome current and future challenges. The future of eye care in the UK is at a precipice. Hospital attendances are increasing year on year,...
Gene therapy for inherited retinal disease: the Manchester Ocular Gene Therapy Group MDT service
4 August 2021
| Jane Ashworth, Tsveta Ivanova, Susmito Biswas, Assad Jalil, Georgina Hall, Rebecca Redmond, Graeme CM Black (Prof), William Newman, Neil Parry, Jane CB Gray, Charlotte Skitterall
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EYE - Paediatrics, EYE - Vitreo-Retinal, EYE - General
The authors describe the process set up in Manchester for the optimum delivery and assessment of a new gene therapy treatment for patients with RPE65 IRD. Inherited retinal dystrophies (IRDs) are the second commonest cause of severe visual impairment in...
