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Microdroplet and splatter contamination during phacoemulsification in COVID-19 era
Half a millilitre of fluorescein was incorporated into 400ml of balanced salt solution to identify microdroplet and splatter from phacoemulsification to simulate possible COVID-19 contamination. Five porcine eyes were mounted to an ophthalmic mannequin head and two surgeons (height 189cm,...Eyes on Rwanda: Lessons from an international ophthalmology experience
On the 26 February 2025, I travelled to Rwanda on the invitation of a former Belfast trainee, Michael Mikhail. Michael is now one of only two vitreoretinal (VR) surgeons in Rwanda, a country with a population of 14 million. Born...
Intravitreal injection related endophthalmitis
This article reviews the incidence, clinical findings, risk factors, management and visual outcomes in intravitreal injection related endophthalmitis. Incidence of this complication is reported to be in the range of 0.038% to 0.065% (1 in 2000-3000 injections). Patients present typically...Guide to Gaining Approval for a Clinical Study
This article focuses on gaining approval for clinical research involving NHS patients, although the principles can be applied to other types of research. The intention is to give an overview of the requirements for setting up a research study, but...
Allergic eyelid dermatitis
This is a retrospective 12 year review of 61 patients diagnosed with periocular allergic dermatitis. The average age was 66 years, with 74% being female. The commonest indications for referral were epiphora, ectropion and blepharitis; and the main symptoms were...
Is exenteration helpful in invasive fungal sinusitis?
Invasive fungal sinusitis is a potentially lethal disease that causes painful orbital apex syndrome with ophthalmoplegia and visual loss. The mechanism of ophthalmoplegia and visual loss is not clear, and neither is the role of radical surgery-orbital exenteration. The authors...
CD73 in aggressive basal cell carcinoma
This is a retrospective review looking at levels of CD73 in aggressive basal cell carcinomas (BCCs) that invade the orbit. Eleven patients who underwent orbital exenteration for invasion by BCCs were compared with 10 matched controls who had simple nodular...
Histopathology-guided management of ocular surface squamous neoplasia (OSSN) with corneal stromal or scleral invasion using ruthenium-106 plaque brachytherapy
This is a retrospective interventional consecutive case series of 42 eyes of 42 patients with OSSN with histopathologically proven corneal stromal and / or scleral invasion following excision biopsy. The mean tumour basal diameter was 9.3mm and thickness of 3.1mm...The increasing privatisation of ophthalmology: How has and how will it affect resident doctors?
It’s well known that the rising number of private ophthalmology providers in the UK have continued to increase their market share in providing various services. Referrals from NHS trusts have continued to increase with nearly 60% of cataract operations being...Oculomics and Big Data changes the game for Medical Ophthalmologists
Oculomics and Big Data changes the game for Medical Ophthalmologists, and here's why.SOS (Simplified Ophthalmic Statistics) Part 4: How to present your statistical analysis
This is the last in this series of short guides which we hope provide some guidance in relation to statistical issues researchers may encounter when conducting research, audit or indeed quality improvement projects. Here we focus on an issue that...
