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Orbis teams up with the Alcon Foundation and OMEGA to improve eyecare in Zambia
The Orbis Flying Eye Hospital returns to Zambia for a three-week training project in Lusaka coinciding with World Sight Day on October 12.Cornea teaching techniques: one cornea donor tissue for two purposes
There is a national shortage in the UK in corneal graft material [1,2]. The majority (69%) of corneal transplants in the UK are partial thickness, with 35% being Descemet membrane endothelial keratoplasty (DMEK) [2]. During the preparation of the donor...Reflections as an international trainee
I had the privilege of undertaking two glaucoma fellowships in the UK – first at the St Paul’s Eye Unit in Liverpool (2022–23), followed by a second year at Moorfields Eye Hospital in London (2023–24). Many of my seniors had...Glaucoma UK announces United Kingdom & Eire Glaucoma Society (UKEGS) Research Award 2024
Glaucoma UK is delighted to announce that this year’s UKEGS Research Award is now open to UKEGS members. The award, funded by Glaucoma UK and UKEGS, offers up to £50,000 for projects aimed at impacting patient care, scientific advancement, or understanding of glaucoma.
Primary intravenous chemotherapy (IVC) for Group D retinoblastoma
A retrospective review is reported of 64 group D retinoblastoma (RB) eyes (52 patients) treated with primary IVC, between 2002 and 2014 from two centres, in the UK and US. The median age at presentation was 11 months, 35 (67%)...
A population based follow-up study on pseudoexfoliation and cataract surgery
n association between pseudoexfoliation (PEX) and cataracts has been shown in many previous studies. Recently, the Australian Blue Mountains Eye Study, using the Wisconsin Cataract Typing and Grading System, observed an increased prevalence of nuclear cataract in eyes with PEX....
PD-1 and retinal ganglion cell death
Death of retinal ganglion cells (RGC) in conditions like glaucoma leads to permanent visual loss. RGC death can be due to the initial stress such as raised intraocular pressure or secondary to mechanism such as oxidative stress. Programmed cell death-1...
Statins inhibit TGFβ2 mediated fibrotic response in astrocytes
Glaucoma is a common condition where increased ocular pressure can lead to death of retinal ganglion cells due to impaired drainage of fluid from the eye. One mechanism involved in glaucoma is remodelling of the extracellular matrix at the lamina...
Somatostatin protects retinal pericytes
Diabetic retinopathy (DR) is a complication of diabetes, caused by high blood sugar levels damaging the retinal microvasculature. Mechanisms, such as oxidative stress and deposition of advanced glycation end products, leads to glial cell activation and neuronal apoptosis. Pericytes, contractile...
Brn3b neuroprotective effect in rat glaucoma model
An adeno-associated virus-directed overexpression of the Brn3b protein in hypothesised to confer neuroprotective effects in this paper. This is ultimately tested in a well-accepted rat glaucoma model (Morrison’s model: saline injection into episcleral veins of rat eyes with a force...
Prognosticating ocular adnexal lymphoma
The authors retrospectively analyse 160 patients with primary ocular adnexal lymphoma to determine the accuracy of prognosis based on the Ann Arbor classification and how this compares to the accuracy of prognosis based on retrospectively applying the newer Tumor, Node,...
