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834 results found

Normative reference values for optic nerve sheath diameter in children

The purpose of this study was to measure optic nerve sheath diameter (ONSD) in paediatric patients without pathology using brain CT performed for various reasons and to provide normal tomographic reference values. This was a retrospective study of CT scans...

Anti-myelin oligodendrocyte glycoprotein antibody positive optic neuritis: a retrospective medical records review

Optic neuritis causes acute loss of visual function and can result in devastating visual dysfunction. Recently, measurements of anti-aquaporin 4 (AQP4) and anti-myelin oligodendrocyte glycoprotein (MOG) antibodies have become available, making it possible to evaluate the disease pathogenesis. This paper...

Longitudinal findings in children with neurofibromatosis type 1

This retrospective chart review evaluates the ophthalmologic findings of children with neurofibromatosis type 1 (NF1). Optic pathway gliomas (OPGs) are the most common tumours found in children with NF1. Findings are compared between eyes with and without optic pathway gliomas...

A novel parameter for angle closure

This is a population cross-sectional study of 464 eyes that underwent swept-source optical coherence tomography (SSOCT) imaging in the dark. Eight out of 128 cross-sectional images were selected for analysis. Matlab was used to measure the iridolenticular contact area (ILCA),...

Infliximab in treatment of PVR

In this phase 2 randomly controlled trial, 66 patients with primary rhegmatogenous retinal detachment and grade C proliferative vitreoretinopathy (PVR) were randomised in a 1:1 ratio to undergo pars plana vitrectomy (PPV) and silicone oil (SO) injection with or without...

How the thinking machine is transforming the retinal landscape

Regulatory approval of the first two therapeutic substances for the management of geographic atrophy (GA) secondary to age-related macular degeneration has been a major breakthrough. The authors explored the issue surrounding the lack of agreed therapeutic standards and diagnostic tools...

Clinical characteristics and visual outcome of patients with macular pseudohole

This is a retrospective study of consecutive patients with macular pseudohole (MPH) who had vitrectomy and were followed for at least 6 months postoperatively. MPH was diagnosed based on spectral-domain optical coherence tomography (OCT) findings. 76 eyes of 75 patients...

Corneal Tissue Addition Keratoplasty

Corza Medical has launched a dedicated CTAK (Corneal Tissue Addition Keratoplasty) instrument set, developed in partnership with CorneaGen, to support surgeons performing this approach to keratoconus treatment. CTAK is an intrastromal lamellar keratoplasty procedure using preserved donor corneal tissue, custom...

Genetic cause for idiopathic foveal hypoplasia

The authors present a small cohort study of 19 patients with idiopathic foveal hypoplasia diagnosed based on optical coherence tomography (OCT) features. Peripheral blood samples from all 19 patients underwent next-generation sequencing and 33 genes known to be involved in...

Grading of ocular inflammation in uveitis: an overview

Anterior uveitis is the commonest form of uveitis, which can lead to severe morbidity if not treated appropriately [1]. Data from general ophthalmology practices suggest around 90% of uveitis encountered by comprehensive ophthalmologists is anterior uveitis [2]. Intermediate (vitreous), posterior...

Mastering clinical skills in ophthalmology

To young junior doctors, and some senior doctors who may not have had much exposure to ophthalmology, the specialty can seem very foreign. Not only are the conditions and examination findings specific to the eyes, but the skill set required...

Clear sight is ‘revelation’ for Yaxley resident following ‘life-changing’ surgery

Retiree Steve Low has rekindled his love for photography.