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1217 results found

Efficacy and safety of intravitreal aflibercept injection in wet age-related macular degeneration

This is a sub-group study of double masked review of patients randomised to different dosages and treatment frequency compared between aflibercept and ranibizumab treatment. This is to evaluate the efficacy and safety of intravitreal aflibercept (IVT-AFL) in Japanese patients with...

Corporate M&A pace gathers momentum

Intensifying franchise competition, maturing product development pipelines and looming loss of exclusivity spur renewed merger and acquisition (M&A) activity in the ophthalmics sector. Rod McNeil reviews recent deals and related strategic developments. AbbVie to acquire Allergan in $63 billion mega-combination,...

Doctor in the House

“What’s the bleeding time?”“10 past 10 sir”. These are the famous lines uttered by Chief Surgeon Sir Lancelot Spratt (James Robertson Justice) and Medical Student Simon Sparrow (Dirk Bogarde) on a pre-op ward round at the fictional St Swithin’s Hospital,...

New webinar series on sight loss and genomic research

A new webinar series highlighting the latest scientific developments and the future of research will be launched next week.

LASIK for myopia progression

The authors hypothesise that corneal reshaping with refractive surgery could have an effect on myopic progression similar to that of orthokeratology because it results in changes to the central cornea and not to the peripheral cornea. This was a retrospective...

Healthcare insurance influence on surgical outcome

This study sought to determine whether outcomes for simple horizontal strabismus surgery differed for children with supported medical assistance (MA) compared to children with private healthcare insurance, with an assumption of lower socioeconomic status (SES) in the MA group. This...

Superior oblique sagittalisation

This paper reports two cases with anomalous posterior course of the superior oblique tendon with insertion nasal to the superior rectus tendon. Both presented with Brown syndrome-like clinical scenarios. The cases were a five-year-old female and four-year-old male. Diagnosis was...

Changing surgery trends from 2009–2020

This paper reports a review of the number and type of surgeries over one decade in a Portuguese hospital. This was a retrospective review of 2050 surgeries. About 70% were strabismus surgery and the remainder included anterior segment and retinopathy...

My top five: Innovative approaches to dry AMD

Age-related macular degeneration (AMD) is one of the leading causes of irreversible blindness in the developing world with its prevalence rising alongside age. In societies characterised by ageing populations, it is imperative we explore more effective treatment to alleviate the...

My Top Five: Innovative approaches to dry AMD

Age-related macular degeneration (AMD) is one of the leading causes of irreversible blindness in the developing world with its prevalence rising alongside age. In societies characterised by ageing populations, it is imperative we explore more effective treatment to alleviate the...

Femto-DMEK – a solution for high re-bubbling rates?

This retrospective study examined results of patients that underwent femtosecond laser enabled descemet membrane endothelial keratoplasty (DMEK) (FE-DMEK) and manual DMEK (M-DMEK) for Fuch’s endothelial dystrophy. In FE-DMEK femtosecond laser was used to create 8.25mm descemetorhexis, whereas during M-DMEK- descemetorhexis...

New mouse model of diabetes mellitus

Diabetic retinopathy (DR) is a serious complication of diabetes. It is driven by the loss of pericytes, cells which control vascular function, due to excess formation of sugar alcohols by the enzyme aldose reductase (AR). AR has been shown to...