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PACK-crosslinking for infectious keratitis

Corneal cross-linking with riboflavin and UV-A light (CXL) is a technology that has been initially developed to treat corneal ectatic disorders [1]. Its effect in stabilising diseases such as keratoconus was reported in numerous trials with excellent long-term outcomes and...

Assessing everyday visual function in dry AMD – what matters to the person?

Age-related macular degeneration (AMD) is the primary cause of blindness in the developed world and is accountable for more than one half of sight impairment registrations within England and Wales [1]. AMD is prevalent in people aged 60 years and...

Gene therapy for inherited retinal disease: the Manchester Ocular Gene Therapy Group MDT service

The authors describe the process set up in Manchester for the optimum delivery and assessment of a new gene therapy treatment for patients with RPE65 IRD. Inherited retinal dystrophies (IRDs) are the second commonest cause of severe visual impairment in...

Sustainability in eyecare: Intraocular gases and the climate emergency

In 2020 the NHS became the first national health system to commit to delivering ‘net zero’ carbon emissions by 2040. The author investigates how the impact of ophthalmic surgery can be reduced. Medical gases have been used in ophthalmic surgery...

Two cases of acute syphilitic posterior placoid chorioretinitis

Syphilis has re-emerged as a significant public health concern, with the World Health Organization (WHO) estimating that 8 million adults aged 15–49 acquired syphilis in 2022. Untreated syphilis can have severe consequences, including cardiovascular, neurological and ocular complications. Ocular manifestations...

OCT in neuro-ophthalmology: A practical overview

From multiple sclerosis to raised intracranial pressure, optical coherence tomography is transforming how we diagnose, monitor and predict outcomes across the full spectrum of neuro-ophthalmic disease. Optical coherence tomography (OCT) is a rapid imaging method that utilises light waves to...

The unlabelled syringe: An avoidable medication risk in ophthalmic surgery

Ophthalmic surgery is a specialty of small volumes, clear fluids and unforgiving anatomy. In cataract, glaucoma and vitreoretinal surgery, a theatre trolley may contain several syringes that look almost identical: balanced salt solution (BSS), lignocaine, intracameral mydriatic, phenylephrine, antibiotic, dye,...

Capacity-building through the COECSA-RCOphth LINK – linking journals in a training and mentorship programme

The College of Ophthalmology of Central, Eastern and Southern Africa (COECSA) [1] and the Royal College of Ophthalmologists (RCOphth) [2] have a long-standing health partnership through the VISION 2020 LINKS Programme [3,4]. The LINK started a new project in 2019...

Protecting retinal ganglion cells

Glaucoma is considered to be a heterogeneous group of conditions giving retinal ganglion cells (RGC) damage. Lowering intraocular pressure (IOP) reduces the risk of progressive RGC loss in glaucoma. Regeneration of the optic nerve has been shown to restore some...

Four key questions and answers for glaucoma practitioners

In this discussion paper the authors pose four questions for the clinician diagnosing and monitoring glaucoma, and supply evidence-based answers. Worldwide, the most common functional test used to diagnose and monitor glaucoma is static automated perimetry, most typically with a...

“Herr Doktor, I can’t see but I am driving”

This 56-year-old lady was quite puzzling. With her own glasses and the pinhole she merely managed to see the 1.3 and 1.0 logMAR lines with her right and left eye, respectively (I am currently working in Germany again, so goodbye...

The role of injection assistant devices in establishing a nurse-led AMD service

The author shares his experience of setting up a nurse-led service to deliver anti-VEGF intravitreal injections and how injection assistant devices supported training. Age-related macular degeneration (AMD) has become a leading cause of irreversible blindness [1]. It is estimated that...