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Hot debates in medical retina and imaging: Perspectives from the Controversies in Ophthalmology 2020 virtual conference

5 August 2020 | | EYE - Vitreo-Retinal, EYE - Imaging, EYE - General
Controversies in medical retina and imaging were debated during the Controversies in Ophthalmology 2020 virtual conference held during two mid-day scientific sessions on 27 and 28 March 2020. The author recounts key perspectives and presents viewpoint recommendations from the Vision...

Subthreshold micropulse laser treatment in chronic central serous chorioretinopathy

1 February 2016 | | EYE - Vitreo-Retinal
This retrospective study was conducted to assess the treatment of 38 patients of chronic central serous chorioretinopathy with a 577-nm subthreshold micropulse laser (SML) Supra Scan Quantel Medical. Eighteen patients of these had persistent subretinal fluid (SRF) after photodynamic therapy....
Ophthalmologica journal cover image

OCTA in geographic atrophy

4 August 2021 | | EYE - Vitreo-Retinal | Age-related macular degeneration, Angiography, Choriocapillaris, Choroid, Optical coherence tomography
In this article the authors aim to give an overview of the current literature concerning the application of OCT-A in geographic atrophy (GA). GA is a disease characterised by loss of outer retinal layers including photoreceptors, degeneration of the retinal...

Importing iron to the retina

1 October 2017 | | EYE - Vitreo-Retinal
In the retina, iron is particularly critical for the visual phototransduction cascade. In the retinal pigment epithelium (RPE), RPE65 activity leads to 11-cis-retinaldehyde, the photosensitive component of rhodopsin production and iron containing enzymes are necessary for disc replacement in photoreceptor...

Role of fundus autofluorescence patterns and baseline atrophy area on geographic atrophy progression

1 December 2014 | | EYE - Vitreo-Retinal
Central geographic atrophy (GA) is one of the morphological sub types of late-stage macular degeneration. The natural course of the disease is characterised by expanding areas of macular atrophy, which cause absolute scotoma. Fundus autofluorescence (FAF) is derived from lipofuscin...

Microperimetry of subretinal drusenoid deposits

1 February 2014 | | EYE - Vitreo-Retinal
Subretinal drusenoid deposits (SDD), originally termed ‘reticular pseudo-drusen’, have recently been identified by histology and optical coherence tomography (OCT) as aggregations located in the subretinal rather than the sub retinal pigment epithelium (RPE) space. These deposits affect the amount of...

Macular pigment and dark adaptation in older population with normal maculas

1 December 2018 | | EYE - Vitreo-Retinal
Macular pigment (MP) such as lutein, zeaxanthin and meso-zeaxanthin are highly concentrated in the fovea. They protect the retina from damage of ambient blue light via antioxidant properties. In older eyes with normal healthy retina, macular pigment optical density (MPOD)...

Belfast briefing: Retina Day roundup from the RCOphth 2024 Annual Congress

2 August 2024 | | EYE - General
Belfast hosted this year’s Royal College of Ophthalmologists’ (RCOphth) Annual Congress, a meeting dedicated to sharing advances, knowledge and clinical practice points in ophthalmic care. This article summarises selected talks by medical and surgical retina specialists during the Retina Subspecialty...

Pigmented paravenous retinochoroidal atrophy

4 December 2024 | | EYE - Imaging, EYE - Vitreo-Retinal
Presentation A 46-year-old Caucasian female was referred to the eye clinic by her local optician following a routine sight test. She was noted to have pigmentary retinal changes in both eyes but was asymptomatic with no visual complaints. At presentation...

A new observation point: updating the nomenclature and classification with OCT

3 June 2021 | | EYE - Imaging, EYE - Vitreo-Retinal, EYE - General
The evolution of ophthalmic imaging technologies has been particularly rapid over the last few years. The author provides an update of the current terms for common signs and pathologies observed using optical coherence tomography. My experience as an ophthalmic technician,...

Effect of minor trauma in eyes with previously undiagnosed angioid streaks

1 April 2014 | | EYE - Cataract, EYE - Cornea, EYE - General, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal
Angioid streaks (AS) may be associated with pseudoxanthoma elasticum (PXE), Paget’s disease, haemoglobulinopathies, Ehlers-Danlos Syndrome or abetalipoproteinaemia. Histopathology showed retinal pigment epithelium (RPE) and choriocapillaris loss, elastic fibre degeneration, calcium deposition, active choroidal neovascular membrane (CNVM) and vascular endothelial growth...

The challenge of chorioretinal folds in virtual eye clinics

3 June 2024 | | EYE - Vitreo-Retinal, EYE - Orbit
Chorioretinal or choroidal folds are parallel striations involving the retina, retinal pigment epithelium (RPE), Bruch’s membrane, and inner choroid [1]. They can arise from compressive stress on these layers, and their presence often serves as a diagnostic marker for underlying...