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AMD and visceral fat and pro-inflammatory factors
Several large studies have shown a positive relationship between age-related macular degeneration (ARMD) and high body mass index. The waist-hip ratio is also associated with development of early AMD. Visceral fat has a pro-inflammatory effect, which means it has an...
Allografts in limbal stem cell deficiency
This prospective comparative study compared outcomes of live related limbal allograft (Lr-CLAL) versus cadaveric keratolimbal allograft (KLAL) in limbal stem cell deficiency secondary to ocular burns. Twenty patients were randomly allocated into each group. The Lr-CLAL group had a significant...
Cytotoxic effect of voriconazole on human corneal epithelial cells
Voriconazole is a second-generation synthetic derivative of fluconazole with broadened antifungal spectrum. It is becoming the drug of choice for fungal keratitis. Voriconazole eye drops are not available commercially, thus have to be prepared by diluting the intravenous formulation containing...
A case series of acquired esotropia in cerebellar disease
Acquired esotropia in cerebellar disease is well described but under-recognised. The pathogenesis of cerebellar esotropia is controversial. It is suggested it may be a result of disruption to central vestibular pathways. This article reports a case series of seven adults...
A case of progressive supranuclear palsy-like syndrome following aortic aneurysm repair
This original article illustrates the case of an 18-year-old woman who developed progressive supranuclear palsy-like syndrome following an uneventful aortic aneurysm repair. The patient was unaffected for the first 48 hours after surgery and then developed dysarthria, dysphagia (requiring a...
Dyslexic reading improved by vergence training
The aim of this study was to evaluate if reading performance could be improved by a period of compensatory vergence training in dyslexic children with otherwise normal binocular vision. The study included 13 children with dyslexia – mean age of...
Binocular summation with low contrast
The magnitude of binocular summation was investigated in normal control subjects using four different letter charts of varying type with fixed and variable contrast levels and spatial frequency to determine which tests most readily reveal binocular summation in normal subjects....
BT for intermittent exotropia
This study aimed to evaluate the effect of botulinum toxin (BT) on the amount of deviation and fusional control state of intermittent exotropia. Twenty-one patients (five male and 16 female) aged five to 18 years with progression of exotropia were...
Closed-chamber haptic re-externalisation for posteriorly displaced sclerotomy and inadequate haptic tuck in glued posterior chamber intraocular lenses
This technique (online video http://jcrsjournal.org) emphasises the importance of both symmetrical and sufficient anterior placement of sclerotomies to externalise an adequate length of the haptics, which in turn provides good centration and stability of the intra-ocular lens (IOL). The authors...
Optic nerve head perfusion response to reduced blood pressure and increased intraocular pressure
The purpose of this prospective study was to test the hypothesis that blood flow autoregulation in the optic nerve head has less reserve to maintain normal blood flow where there is a blood pressure induced decrease in ocular perfusion pressure...
Surgical outcomes in third nerve palsy
The authors of this article explore the factors associated with successful surgical outcomes in third nerve palsy, which is known to be difficult to treat. A number of case notes were reviewed for patients who underwent surgery or botulinum toxin...
