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836 results found

Atopic keratoconjunctivitis (AKC) and ocular surface squamous neoplasia (OSSN)

The authors present two cases of invasive OSSN in patients with severe AKC. Case 1 was a 73-year-old male with severe AKC and atopic eczema who developed a suspicious papillary-like limbal lesion in the left eye. He had an excisional...

IAC vs. IVC chemotherapy for RB

This a single centre retrospective review of consecutive patients between 1997 and 2014, of all sporadic unilateral retinoblastoma (RB) group D cases, treated with combined intravenous chemotherapy (IVC) and focal treatments (1997- 2008), or intra-arterial chemotherapy (IAC) treatment (2008 to...

Medial rectus anatomy in exotropia

This study investigates the differences between extraocular muscles in patients with intermittent exotropia and normal controls regarding muscle fibre arrangement and diameter, and distribution and activation of satellite cells. Fifteen patients were recruited having medial rectus resection surgery. Resection sections...

Diplopia after orbital decompression

This is a review of patients undergoing a balanced two-wall and fat orbital decompression to identify risk factors for new onset diplopia. Standard decompression techniques were used, but as the surgery was conducted by ENT surgeons, the medial walls were...

Incomplete teprotumumab treatment for thyroid eye disease

This is a multi-centre retrospective analysis of clinical outcomes in patients who were on teprotumumab for thyroid eye disease but had the usual regime of eight infusions, three weeks apart, interrupted due to COVID-19. Manufacturing was suspended between Dec 2020...

Rare presentation of giant cell arteritis in Chinese subjects

Only a few case reports of biopsy-proven GCA (BpGCA)-associated vision loss in Chinese subjects have been published. This paper presents three elderly Chinese subjects with BpGCA who presented with vision loss. A search of the literature was also conducted to...

Using modified staging criteria to determine optic nerve invasion in retinoblastoma

This paper reports the use of a modified staging criteria for optic nerve invasion in extraocular retinoblastoma and its correlation with treatment outcomes in 21 patients. The average age at presentation was 41 months (7–120) and there were 14 unilateral...

Features of bacterial orbital cellulitis on MRI imaging

This multi-centre retrospective study from Australia and the UK examined the quantitative and qualitive parameters of magnetic resonance imaging (MRI) imaging in bacterial orbital cellulitis. Twenty MRI scans from 20 patients with pre-septal and orbital fat involvement (mean age: 40.8...

My Top Five: Innovations in the diagnosis of ocular tumours

Ocular tumours can vary widely in origin, from benign growths to metastases from distant disseminated malignancies. Although rare, ocular tumours pose a significant health and economic burden globally, with ocular cancers accounting for 0.2% of all diagnosed malignancies in the...

Surgical treatment of high myopia

Although several excellent modalities are available for correcting high myopia, the surgical treatment of this condition remains one of the biggest challenges for refractive surgeons; this group of patients is often very dependent on contact lenses. If these patients become...

Strabismus in thyroid eye disease

Pathogenesis Thyroid eye disease (TED) is an auto-immune condition, in the initial phase there is lymphocytic infiltration and oedema of the extraocular muscles with deposition of glycosaminoglycans and hyaluronic acid and adipogenesis, which can lead to an increase in the...

Spot screener versus Grand Seiko measurements

The authors aimed to determine repeatability and reproducibility of refractive values and pupil size measured using the Spot Vision Screener and to compare its measurement values with the Grand Seiko autorefractor. This was a cross-sectional study of 22 healthy adults;...