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Ocular mucous membrane pemphigoid: the importance of early detection and treatment

Mucous membrane pemphigoid (MMP) is an autoimmune blistering disorder that is characterised by subepithelial bullae. The ocular manifestation of MMP, ocular mucous membrane pemphigoid (OMMP), is a sight-threatening condition characterised by conjunctival cicatricial changes associated with corneal vascularisation and scarring....

Getting started in ophthalmology: Advice for new doctors

Starting your first rotation in ophthalmology is exciting and a little daunting. As the start date approaches, the nerves may start to creep in. What’s expected of me? How much ophthalmology am I supposed to know? How will the on-calls...

Empowering primary care patients registered blind or partially sighted

With two million people in the UK living with visual impairment [1], being able to provide equitable and effective communication to this group of patients is essential in primary care. Yet, as highlighted by research conducted by Sight Loss Councils,...

The structure function relationship in glaucoma

Chronic open angle glaucoma (COAG) is the second most common cause of blindness worldwide. It is diagnosed on the basis of three clinical signs, raised intraocular pressure (IOP), visual field (VF) defects and structural changes to the optic nerve head...

Emerging developments in dry eye

An estimated 344 million people worldwide suffer from dry eye [1]. This chronic syndrome is characterised by a vicious cycle of tear film hyperosmolarity, tear instability and corneal stress, leading to increased friction, inflammation, ocular surface damage and decreased visual...

Management of retinal diseases: highlights from the AAO 2019 Retina Subspecialty Day Meeting

The author highlights current debate, opinion and late breaking developments in the management of retinal diseases. The American Academy of Ophthalmology’s 2019 Retina Subspecialty Day Meeting was held on 11-12 October, 2019 in San Francisco, USA. Established and emerging innovative...

Glaucoma and erectile dysfunction

In this cross-sectional study with patient questionnaire and retrospective chart review, a total of 167 male patients over 40 years of age were enrolled. Exclusion criteria included previous exposure to radiation and surgical treatment for prostate benign hypertrophy or malignancy....

Association between serum levels of testosterone and estradiol with meibomian gland assessments in postmenopausal women

This study aims to reveal any correlation between serum levels of testosterone and estradiol in postmenopausal women with meibomian gland dysfunction. Postmenopausal subjects were defined as amenorrhoea for at least one year with low follide stimulating hormone (FSH) and estradiol....

Association between serum 25-hydroxyvitamin D levels and age-related cataracts

Cataractogenesis occurs as a result of ageing, smoking, exposure to UV radiation and genetic predisposition. Antioxidants can reduce the cataract risk as found in animal models and humans and vitamin D is one of them. This epidemiological study based in...

Oral omega-3 fatty acid treatment for dry eye in contact lens wearers

This study evaluates the effect of dietary omega-3 fatty acid supplementation of dry eye symptoms, tear film tests, and conjunctival impression cytology in patients with contact lens wear-associated dry eye. In this randomised double-blind, multi-centred trial, contact lens wearers (n=...

Intravitreal dexamethasone implant for diabetic macular oedema

The authors report on the three-year outcomes of the Ozurdex Dexamethasone (DEX) intravitreal implant multi-centre trial for the treatment of diabetic macular oedema (DME). Patients with DME (best-corrected vision of 20/50 to 20/200 and central retinal thickness of ≥300µm) were...

Non-contact-lens-associated acanthamoeba keratitis

This retrospective study was done to study the clinical presentation and microbiological results of non-contact-lens-related acanthamoeba keratitis (AK). One hundred and ninety-four patients with microbiological / histopathological diagnosis of AK over four years were included. All patients had corneal scrapings...