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Exploring the potential of neurodegenerative disease screening within age-related eye disease research

The authors recruited healthy controls aged between 60 and 75-years-old, previously enrolled into a registry as patients following cataract surgery without age-related macular degeneration (AMD). Exclusion criteria included dense cataract, retinal disease, ocular inflammatory disease, moderate glaucoma, optic neuropathy, cancer,...

Blood pressure association with primary open angle glaucoma severity

This prospective observational study involved 47 patients diagnosed with primary open angle glaucoma (POAG) examined to investigate their postural blood pressure response and its potential correlation with the severity of glaucomatous optic neuropathy (GON). Participants underwent intraocular pressure and systemic...

Inner nuclear layer of the retina showing increase in thickness in diabetic macular oedema

Diabetic retinopathy is one of the leading causes of blindness in the developed world. With optical coherence tomography (OCT), it has become possible to image the retina in vivo and to measure retinal oedema by measuring retinal thickness (RT) with...

Migraine attack: does retinal and peripapillary blood flow change?

This prospective clinical study compared retinal and peripapillary blood flow parameters in migraine patients during an attack with healthy controls using optical coherence tomography angiography (OCTA). OCTAs were performed on 52 eyes from 26 migraine sufferers and 48 eyes from...

Treatment outcomes for retinal detachment

This is a retrospective, nationwide, multicentre study with retinal detachment (RD) in the Japan-RD registry between 2016 to 2017. The primary outcome was the estimated mean difference of postoperative corrected visual acuity (CVA) in six months and a propensity score...

Silicone oil (SOT) versus gas (GT) tamponade for primary rhegmatogenous retinal detachment treated successfully with a propensity score analysis

This is a retrospective, nationwide, multicentre study with retinal detachment (RD) in the Japan-RD Registry between 2016 to 2017. The primary outcome was the estimated mean difference of postoperative cerebral vascular accident (CVA) in six months and a propensity score...

Review of non-arteritic anterior ischaemic optic neuropathy

This article reviews the risk factors, clinical presentation and therapies that have been investigated for non-arteritic anterior ischaemic optic neuropathy (NAAION). Additionally, it provides an update from recent rodent and primate models, offering a new insight into the pathophysiology of...

Current literature evidence for fulminant idiopathic intracranial hypertension

Fulminant idiopathic intracranial hypertension (IIH) is a rapid vision-degrading presentation of IIH with limited published studies. This narrative review aims to collate current knowledge around fulminant IIH presentation and visual outcomes. Search terms included IIH, benign intracranial hypertension, or pseudo-tumour...

Septo-optic dysplasia – a case note review

Septo-optic dysplasia (SOD) is a congenital disorder belonging to the midline brain malformation group. The condition manifests as a classical triad, including optic nerve hypoplasia (ONH), agenesis of midline structures (absent septum pel-lucidum and agenesis of the corpus callosum), and...

Visual snow syndrome: a review

Visual snow syndrome (VSS) is a neurological condition characterised by visual phenomena described as dots moving across the visual field. Other visual symptoms can take the form of palinopsia, entopic phenomena, photophobia and nyctalopia. Tinnitus and migraine can be commonly...

Complications of orbital cavernous venous malformation excision

This is a review of 290 patients who underwent excision of orbital cavernous venous malformations (OCVM) between 1970 and 2021, looking to identify the risk factors for a poor visual outcome following surgery. Intraconal lesions were classified as Group I,...