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1452 results found

Do steroids prevent progression to proliferative diabetic retinopathy (PDR)?

There is continuing debate on the merits of pan-retinal photocoagulation (PRP) for severe pre-proliferative and proliferative DR versus the newer therapies that inhibit vascular endothelial growth factor (VEGF). This has been hotly debated [1] following the publication of findings from...

The management of retinal vein occlusions: a summary

Retinal vein occlusions (RVO) are the most common cause of visual loss from retinal vascular disease second to diabetic retinopathy. Vision is lost due to ischaemia, macular oedema and / or haemorrhage which ultimately effects a patient’s quality of life...

An unusual case of silicone oil in the anterior chamber simulating intraocular implant

Silicone oil internal tamponade has been used for over 50 years, even prior to pars plana vitrectomy [1].Over a course of time silicone oil may migrate to the anterior chamber through the pupil. This may disperse in the form of...

An update on inherited retinal disorders (part 1) – overview and assessment of inherited retinal disease

Part 2 of this topic can be found here Inherited Retinal Disease (IRD) is the leading cause of blindness certification in the working age population (age 16-64 years) in England and Wales and the second most common in childhood [1]....

Risk factors for ocular complications following orbital fractures

In this Japanese retrospective cohort study, the authors examined records of 416 consecutive orbital fracture patients treated over a 10-year period at a single institution. The study identified ocular complications occurring in 9.5% of the cases, with traumatic mydriasis, hyphaemia...

Correlation between anti-retinal antibodies and proliferative vitreoretinopathy (PVR)

The pathological basis of PVR is not clearly understood and there are no effective medications targeting this condition. This cross-sectional study looked at the possible association of anti-retinal antibodies with patients with PVR and retinal detachment (RD). Aqueous and vitreous...

RPE tears after intravitreal Lucentis

The current hypothesis regarding retinal pigment epithelium (RPE) tears is the contraction and fibrosis in choroidal neovascularisation (CNV) tissue after anti-VEGF therapy can induce rips in the overlying RPE. This South Korean study aimed to identify the association between RPE...

Ginko bilboa extract affects hypoxic retinal pigment epithelial cells

Wet age-related macular degeneration (AMD) is characterised by choroidal neovascular membrane (CNVM) formation. It is thought that localised hypoxia within the retina results in overexpression of growth factors such as vascular endothelial growth factor (VEGF), which induces CNVM formation. VEGF...

OCTA in diabetic macular oedema treated with intravitreal aflibercept (DOCTA Study)

Central vision loss due to diabetic macular oedema (DME) can be attributed not only to presence of the macular oedema itself but also, in some cases, to alterations of the foveal avascular zone (FAZ). The DOCTA trial was a longitudinal,...

AI breakthrough in detecting leading cause of childhood blindness

An artificial intelligence (AI) tool could be an effective way of identifying retinopathy of prematurity (ROP), the leading cause of childhood blindness in middle-income countries, finds a new study led by UCL and Moorfields Eye Hospital researchers.

SCONe Project seeks participants for patient and public involvement group to revolutionise AMD research

The SCONe project, run by optometrists, ophthalmologists, and researchers from the University of Edinburgh, and funded by Sight Scotland, is appealing for participants to take part in a Patient and Public Involvement (PPI) group focused on revolutionising the detection and management of Age-Related Macular Degeneration (AMD).

AI predicts eye damage from autoimmune drug, years before symptoms appear

A novel AI tool could transform screening for patients taking hydroxychloroquine by spotting early signs of eye damage, according to a study published in Opthalmology Retina. Researchers have devised an artificial intelligence (AI) system that can detect and predict serious...