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Cambridge Ophthalmological Symposium 2024: Evolution and the Eye

by Anushka Irodi, Y5 Medical Student, University of Cambridge, UK. The 52nd Cambridge Ophthalmological Symposium, a renowned two-day national meeting, took place on September 5th and 6th, 2024 at St John’s College, Cambridge, UK. It brought together international leading minds...

Tackling diabetic retinopathy globally through the VISION 2020 LINKS Diabetic Retinopathy Network

It is abundantly clear that the burden of diabetes is rapidly increasing, as there are now 415 million adults with diabetes in the world, with a projected rise to 642 million by 2040 [1]. This equates to 1 in 10...

Back-to-back congresses in Africa highlight international collaboration to advance eye health

The ISOO Africa 2023 Congress The first International Society of Ocular Oncology (ISOO) [1] conference to be held in Africa took place in Mombasa, Kenya, from 21-23 August 2023. Participants came from all over Africa, as well as the US,...

Novel retinal pigment metric tackles bias in AI models

Researchers have developed an innovative metric for objectively classifying pigmentation in a retinal image, rather than using subjective social constructs like ethnicity or other demographic variables, as is currently the case when building health datasets. Called the Retinal Pigment Score...

Recognising responsibility, breakthrough design

Celebrating achievements in the international optical world, the 30th anniversary of the Silmo d’Or Awards was a spectacular event. Eyewear designers, international media and senior optical executives and VIPs were welcomed to the underground halls of the Carrousel du Louvre...

Choroideremia in women

The authors report a questionnaire-based study of female carriers of choroideremia, an X-linked inherited chorioretinal dystrophy. As an X-linked condition the full clinical features are predominantly seen in men but a proportion of women suffer some morbidity, likely due to...

Keratoconus: When, Why and Why Not. A Step by Step Systematic Approach

This is a single author publication addressing the subject of ectatic corneal disorders and keratoconus (when, why, and why not) with a step by step systematic approach to management using modern sophisticated diagnostic and screening tools. It is comprised of...

Preoperative RPE alterations in macular holes

This retrospective interventional case series from Japan assessed whether preoperative alterations of the retinal pigment epithelial (RPE) in idiopathic macular holes correlated with postoperative functional and morphological changes in the macula. Fifty-nine eyes had preoperative Spectralis OCT using the ‘detailed’...

Retinoblastoma chemotherapeutic drugs and their toxic effects on RPE cells

There is reported clinical evidence of retinal pigment epithelium (RPE) alterations after intra-arterial (IAC) and intravitreal chemotherapy (IViC) of retinoblastoma. The purpose of this study was to investigate the cellular toxic effects of melphalan, topotecan and carboplatin on the RPE...

Effect of anti-VEGF treatment on PED morphology

This retrospective study of 30 eyes assessed the effect of anti-VEGF on morphology of pigment epithelial detachments (PED) secondary to age-related macular degeneration (AMD). Thirty eyes of 28 patients with PED were compared to 30 eyes of 30 patients with...

Silicone oil in rhegmatogenous retinal detachment

Silicone oil (SO), used in complicated retinal detachments, is associated with complications such as cataract, increased intraocular pressure (IOP), keratopathy, cystoid macular oedema (CMO), epiretinal membrane (ERM) and loss of vision. Emulsification of oil can also lead to migration of...

Medical treatment of orbital lymphatic malformations

This is a literature review of the use of Sirolimus, to treat orbital lymphatic malformations. Sirolimus is an immunosuppressant used in renal transplants, and acts by inhibiting mammalian target of rapamycin (mTOR), which in turn inhibits activation of T and...