You searched for "ischaemic"
G-CSF intravitreal injections for NAION: a pilot study
5 April 2022
| Su Young
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EYE - Neuro-ophthalmology
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Anterior ischemic optic neuropathy, Granulocyte colony-stimulating factor, Intravitreal injection, Neuroprotection, Optic atrophy
In rodent models with anterior ischemic optic neuropathy (AION), granulocyte colony-stimulating factor (G-CSF) confers a neuroprotective effect on retinal ganglion cells (RGCs) via anti-apoptotic and anti-inflammatory processes. This prospective study investigated the efficacy of intravitreal injection of G-CSF for the...
How common is optic disc drusen in young patients with NAION?
4 August 2021
| Lauren R Hepworth
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EYE - Neuro-ophthalmology
A retrospective notes review at two tertiary care centres was completed between 2009 and 2019. The inclusion criteria for the study was a diagnosis of nonarteritic anterior ischaemic optic neuropathy (NAION) in at least one eye, aged between 18 and...
Retinal vessel diameter in pseudoexfoliation
5 February 2020
| Kurt Spiteri Cornish
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EYE - Vitreo-Retinal
Pseudoexfolation (PEX) is characterised by deposition of fibrillary extracellular material on ocular and extraocular tissue. Studies have shown that deposition in vascular structures cause hypoxia and ischaemia. In the eye, a decrease in blood supply to the optic nerve can...
Transsynaptic retrograde degeneration linked to homonymous visual field loss after stroke
10 May 2024
| Lauren R Hepworth
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EYE - Neuro-ophthalmology
centre, of individuals identified with homonymous visual field loss post ischaemic stroke. Exclusion criteria were bilateral ischaemia, anterior / pregeniculate visual pathway affected and other pathology with the potential to effect visual fields. The following were extracted from the medical...
Unique case of steroid-induced intraocular pressure spike causing NAION
7 April 2021
| Annes Ahmeidat
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EYE - Neuro-ophthalmology
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Herpes zoster, Intraocular pressure, Ischemic optic neuropathy, NAION
The literature describes previous cases of nonarteritic anterior ischaemic optic neuropathy (NAION) following rapid rises in intraocular pressure (IOP) leading to reduced optic nerve head perfusion and disruption. This is commonly following ophthalmic procedures, acute glaucoma or steroid eye drops....
Is it NAION… Now what?
3 April 2024
| Urvi Patel
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EYE - Neuro-ophthalmology
Case presentation We present the case and discussion of a 46-year-old Caucasian male who complained of immediate reduced vision following complicated neck dissection including a total laryngopharyngectomy, free flap reconstruction for a T4N3 squamous cell carcinoma (SCC) of the left...
Isolated trochlear (fourth cranial) nerve palsy in an Asian population
1 August 2018
| Lakana Kumar Thavaratnam, James F (Barry) Cullen
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EYE - Neuro-ophthalmology
The authors report on 35 consecutive new cases of isolated fourth cranial nerve palsy seen over a period of six months in one neuro-ophthalmology clinic in Southeast Asia, with emphasis on their aetiology and management. We report on 35 patients...
Differences in elastometry of cornea and optic nerve head in both eyes of patients with NAION
1 February 2019
| Claire Howard
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EYE - Neuro-ophthalmology
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Corneal hysteresis, corneal resistance factor, non-arteritic anterior ischaemic neuropathy, optic nerve head biomechanics, real-time elastography
Non-arteritic anterior ischaemic optic neuropathy (NAION) is an important cause of visual loss in the middle aged and elderly population. This prospective cross-sectional study investigates the biomechanical properties of optic nerve head (ONH) and cornea in both eyes of patients...
A near miss
A 55-year-old gentleman presented with a ‘blurry patch’ to his left eye which he had noticed for the past two months. The visual acuity with correction was 6/5 in the right eye and 6/6 in the left eye on the...The management of retinal vein occlusions: a summary
1 February 2015
| Amy-lee Shirodkar
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EYE - Cataract, EYE - Refractive, EYE - Cornea, EYE - Imaging, EYE - Vitreo-Retinal, EYE - General
Retinal vein occlusions (RVO) are the most common cause of visual loss from retinal vascular disease second to diabetic retinopathy. Vision is lost due to ischaemia, macular oedema and / or haemorrhage which ultimately effects a patient’s quality of life...
Predicting ischemic lesion location using perimetry
3 August 2023
| Lauren R Hepworth
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EYE - Neuro-ophthalmology
The authors present a retrospective records review, using the search terms homonymous hemianopia, visual field loss and MRI. Only posterior circulation artery territory ischemic strokes were included. Demographics, stroke details and initial and follow-up with 24-2 SITA Standard perimetry results...
