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In conversation with Fares Antaki: The retinal age gap in schizophrenia

Fares Antaki. Nima Ghadiri (NG): The ‘retinal age gap’ (RAG) is a relatively new concept. Based on your study [1], how confident are you in proposing this as a non-invasive, accessible biomarker for accelerated biological ageing in patients with neuropsychiatric...

New webinar series on sight loss and genomic research

A new webinar series highlighting the latest scientific developments and the future of research will be launched next week.

COPHy 2026

17th Annual Congress on Controversies in Ophthalmology

A refractive surprise after vitrectomy and capsulectomy

Figure 1: Right posterior capsule small aperture. We report a case of a pseudophakic patient who underwent vitrectomy and posterior capsulectomy. In spite of good visual acuity and absence of floaters, he was unhappy with the visual outcome. Case report...

Pegcetacoplan: A breakthrough treatment for dry age-related macular degeneration?

Age-related macular degeneration (AMD) is a degenerative condition affecting the macula, the part of the retina responsible for central vision. It is characterised by the presence of drusen and retinal pigment epithelium (RPE) abnormalities in the absence of other macular...

RTP801 as a neuroprotective and axon regenerative treatment

This paper describes the neuroprotective and axon regenerative effects of siRTP801, which is a translatable small-interfering RNA (siRNA) targeting mTOR negative regulator; RTP801, through in-vivo and in-vitro models. In-vivo studies involved an optic nerve crush rat model with intravitreal injections...

Acute retinal necrosis: an Indian experience

The authors of this retrospective study aimed to provide clinical outcomes in 62 eyes of 53 patients presenting with acute retinal necrosis. All eyes received intravenous acyclovir (10mg/kg tds) for 7-10 days followed by oral antiviral therapy (valaciclovir 1g tds...

Air tamponade in pars plana vitrectomy for primary rhegmatogenous retinal detachment repair

The authors report a study aimed to establish the use of air as a tamponade agent for primary rhegmatogenous retinal detachment (RRD) treatment, regardless of the position or the number of retinal breaks. Two hundred and thirty-six eyes of 230...

High-stakes scenarios in retinal vein occlusion: A survey of medico-legal implications

Central retinal vein occlusion (CRVO) is the second most common retinal vascular disease after diabetic retinopathy, and its clinical complexity often intersects with medico-legal scrutiny [1]. Missteps in timely diagnosis, inadequate follow-up or poor documentation can lead to patient harm...

Macular atrophy with aflibercept

The authors of this paper set out to investigate the prevalence of macular atrophy in treatment-naive patients with neovascular AMD undergoing aflibercept monotherapy (three monthly loading injections followed by subsequent treatment every two months). Case notes over a three year...

My top five: Uses of artificial intelligence in ophthalmology

Artificial Intelligence (AI) has emerged as a prominent topic of discussion within the field of ophthalmology, captivating researchers and practitioners alike. Although recent attention has been drawn to the integration of AI in ophthalmology, it’s important to recognise that AI...

My Top Five: Uses of artificial intelligence in ophthalmology

Artificial Intelligence (AI) has emerged as a prominent topic of discussion within the field of ophthalmology, captivating researchers and practitioners alike. Although recent attention has been drawn to the integration of AI in ophthalmology, it’s important to recognise that AI...