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ABCA1 mediates lipid efflux in the retina

Age-related macular degeneration (AMD) is the leading cause of blindness in the elderly population. There are two forms of AMD, dry and wet, the latter so named because of the presence of choroidal neovascularisation. Both forms lead to retinal pigment...

Meibomian gland dropout in patients with dry eyes

In this prospective study 264 patients with symptoms of dry eye were examined with a non-contact meibography system to assess the morphological changes in their meibomian glands. These patients were not previously diagnosed with meibomian gland dysfunction and patients with...

Visual defects in deaf children and young adults

This literature review article serves as a great update on the current evidence relating to visual defects in the young deaf population. There is a good introduction with background information and demographic data relating to UK hearing impairment. The authors...

Differences in elastometry of cornea and optic nerve head in both eyes of patients with NAION

Non-arteritic anterior ischaemic optic neuropathy (NAION) is an important cause of visual loss in the middle aged and elderly population. This prospective cross-sectional study investigates the biomechanical properties of optic nerve head (ONH) and cornea in both eyes of patients...

Paraneoplastic optic neuropathy features

This is a retrospective review of seven patients diagnosed with paraneoplastic optic neuropathy (PON) between January 2015 and June 2017. Five patients had a history of primary malignancy, including papillary thyroid carcinoma, type B thymoma, testicular seminoma and lung carcinoma....

Biometry measure after cycloplegia

The authors investigated optical biometry in an Indian paediatric population on normal and cataract paediatric eyes and studied the effect of cycloplegia on different parameters measured in these eyes. This was a prospective study of 76 eyes aged five to...

The global burden of age-related macular degeneration

Age-related macular degeneration (AMD) is the third leading cause of blindness (behind cataract and refractive error). The authors present the results of the Global Burden of Disease (GBD) 2015 study, which included 195 countries. The disability-adjusted life years (DALY) due...

Screening and adherence to glaucoma care in Enugu, Nigeria

The authors present the findings of a cross-sectional survey of participants diagnosed with glaucoma during free eye screening. A total of 830 participants were screened from two outreaches:182 new glaucoma cases were diagnosed (63 glaucoma and 119 glaucoma suspects). There...

Is myopia protective against progression of diabetic retinopathy?

This population-based cohort study assessed the association of refractive error with the incidence and progression of diabetic retinopathy (DR); 1562 eyes of 860 patients with diabetes and gradable retinal photographs were included. Baseline data was taken between 2004-2009 and follow-up...

Amblyopia risk factors in premature children

The purpose of this study was to determine the incidence and timing of presentation of amblyopia risk factors in premature children during the first three years of life. This was a retrospective study including 145 of 292 premature children. Retinopathy...

Benefit of selenium and vitamin D supplementation in thyroid eye disease

There is some limited evidence of as association between thyroid eye disease (TED) and nutritional deficiencies including selenium and vitamin D. Prior studies show that selenium can reduce TPO-antibody concentrations and improve hypothyroidism and post-partum thyroiditis. Limited evidence also shows...

Choroidal vascularity in NAION

The authors present a cross-sectional, non-interventional study of healthy volunteers and those with non-arteritic anterior ischaemic optic neuropathy (NAION) recruited over a six-month period at a single site. NAION is the most common cause of acute optic neuropathy over the...