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Transcriptomic analysis of ocular tissues
Transcriptomics is defined as the analysis of the complete set of RNA transcripts present in a cell under different circumstances, quiescent versus challenge, by microarray analysis. Comparison of transcriptomes identifies genes that are differentially expressed in different cell populations under...ABDO welcomes a new regional lead for Northern Ireland
The Association of British Dispensing Opticians (ABDO) has welcomed Chris McConnell as the new regional lead for Northern Ireland. Chris McConnell, FBDO, is a dispensing optician based in Belfast with over a decade of experience in the optical industry. His...
Aspheric toric IOL implantation and LRI in eyes with cataracts and astigmatism
This is a prospective study from a single unit to compare the visual outcome of aspheric toric intraocular lens (IOL) implantation and limbal relaxing incisions (LRI) for management of coexisting age-related cataracts and astigmatism. Sixty eyes of 60 patients with...
The choroid in pregnancy
During pregnancy there can be different types of ocular changes including a decrease in corneal sensitivity, increase in central corneal thickness and curvature, decrease in intraocular pressure, central serous chorioretinopathy and ocular blood flow. Advances in ophthalmic imaging devices has...
PERG as a visual prognosticator in chiasmatic tumours
Pattern electroretinogram (PERG) allows assessment of ganglion cell function and may therefore be used to assess anterior visual pathway dysfunction. This prospective non-randomised study assessed PERG before and after surgical removal of tumours in and around the sellar region compressing...
Silicone hydrogel contact lenses versus autologous serum drops for dry eyes in Sjörgen syndrome
A total of 37 patients with Sjörgen syndrome (SS) related dry eyes reporting symptoms on standard therapy with artificial tears and anti-inflammatory drops were evaluated in this trial. They were randomly assigned to additional treatment with either balafilcon A silicone...
Moxifloxacin 0.5% for bacterial keratitis
The authors report on the results of a randomised controlled trial comparing commercially available non-preserved moxifloxacin 0.5% vs. a combination of fortified cefazolin 5% and tobramycin 1.3% in the treatment of moderate bacterial keratitis without perforation. Corneal scrapings were collected...
Evaluation of a service providing sight impairment registration for stroke survivors
This service evaluation study of a hospital single centre stroke service was undertaken to determine reasons for declining sight registration, whether patients feel supported without registration and determine changes needed to improve registration processes. A review of existent data was...How good does my vision have to be to drive this thing? Visual standards for various occupations
We can all picture that moment in clinic: you are about to tell someone that they’re no longer legally able to drive, ready to deploy our ‘breaking bad news’ techniques. For some patients this may have been expected, or they...Addressing childhood blindness in sub-Saharan Africa
In this article, the authors explore paediatric ophthalmology subspecialist fellowship training in African nations south of the Sahara. Until recently, most African ophthalmologists who wished to pursue a subspecialty ophthalmology training fellowship had to go abroad. There is a huge...
Vision loss during Eylea treatment for AMD
This report investigated patients who lost more than two lines of vision despite periodic injections of aflibercept and explored the factors associated with vision loss. One hundred and ninety-six eyes were included in this study over a two year period....
