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DSEK – five year results

This UK based study examined long-term descemet stripping endothelial keratoplasty (DSEK) results, looking at graft survival and endothelial cell losses. Data on 210 grafts were included in analysis. Most frequent indication for DSEK was Fuch’s endothelial dystrophy (81.4%) and 46.3%...

Data update for leading causes of CVI in England and Wales

In this article the authors present an epidemiological update, based on certifiable visual impairment (CVI) registration for figures for sight impairment (SI) in England and Wales from the last report of 2007-2008 to the current data for April 2012 to...

Recurrent thyroid eye disease

This study investigates the incidence of recurrent thyroid eye disease. The authors retrospectively reviewed the records of 415 patients who had been diagnosed with thyroid eye disease between 2006 and 2012. The medical notes were scrutinised for evidence of a...

Incidence and risk factors of late in the bag intraocular lens dislocation

The aim of this study was to identify risk factors for late in the bag dislocation over a 21 year period. Worldwide the incidence varies from 0.05% to 3.0%. In this Swedish study they report an increase in incidence in...

Neighbourhood deprivation and risk of age-related eye diseases

In this large epidemiological study, the authors sought to determine if neighbourhood wealth affects age-related ocular health. In particular they wished to see if there was a correlation between social deprivation and macular degeneration, cataract, diabetes-related eye complications, and glaucoma....

Twenty-four hour IOP patterns in patients with thyroid eye disease (OO/GL)

Elevated IOP in patients with thyroid eye disease (TED) can be caused by restriction and compression of the globe by enlarged extraocular muscles, elevated episcleral venous pressure and increased mucopolysaccharide deposition in the trabecular meshwork. Although previous studies have investigated...

Myopic choroidal neovascularisation

This is a review article summarising the latest myopic CNV (choroidal neovascularisation) literature in the clinical experience and management outcomes for recommendation algorithm. The aetiology of the myopic CNV was discussed by the authors under the heading of the heredo-degenerative...

Outcomes of ‘treat and extend’ for neovascular AMD

The authors report on 24-month outcomes of anti-vascular endothelial growth factor (anti-VEGF) therapy using a ‘treat and extend’ regime for treatment-naïve neovascular age-related macular degeneration (nAMD). Data for this study was collected from the Fight Retinal Blindness observational registry based...

Aqueous humour cytokine levels in PCV and nAMD

This study looks into the possible roles of various cytokines or growth factors in the pathogenesis of exudative age-related macular degeneration (AMD) by comparing aqueous levels of 14 cytokines between eyes with polypoidal choroidal vasculopathy (PCV) and those with neovascular...

Glaucoma prevalence in sleep apnoea

Obstructive sleep apnoea (OSA) is a disorder characterised by brief interruptions of breathing during sleep and results from complete or partial collapse of the pharyngeal airway. This study investigated the prevalence and progression of glaucoma in 39 patients receiving treatment...

Meta-analysis of HLA B27 associated acute anterior uveitis

A literature-based meta-analysis was carried out to look at the various clinical features associated with HLA- B27 acute anterior uveitis (AAU). After an extensive search of literature for HLA B27 uveitis was conducted, 735 results were obtained. Twenty-nine articles were...

Using frequency doubling technology perimetry to identify Alzheimer’s disease early

Alzheimer’s disease is widely reported to be associated with deficits in visual function. Visual disturbances include impaired stereopsis, contrast sensitivity and motion detection. Deficits specific to the magnocellular pathway (MGC) have been identified in Alzheimer’s disease. This article compares the...