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Complement factor B polymorphism and the phenotype of early age-related macular degeneration

The relationship between complement factor H (CFH) and age-related macular degeneration (AMD) is very well known, but other genetic polymorphisms relating to AMD are more poorly understood. This study was designed to investigate the relationship between complement factor B (CFB)...

Correlation between anti-retinal antibodies and proliferative vitreoretinopathy (PVR)

The pathological basis of PVR is not clearly understood and there are no effective medications targeting this condition. This cross-sectional study looked at the possible association of anti-retinal antibodies with patients with PVR and retinal detachment (RD). Aqueous and vitreous...

Beginning to flag

Have you signed the petition yet?” the nurse asked me. I am generally a type of person who signs a lot of petitions whilst being cynical that they do anything at all for anyone, including the person who signs them,...

100 years of insulin

*Joint first authors The centenary of the discovery of insulin is a time to celebrate one of the most significant scientific discoveries of the 20th century. Background Before 1923, Type 1 diabetes mellitus [T1DM] resulted in death from severe ketoacidosis...

My journey as advanced ophthalmic emergency nurse practitioner

Grace Eni explores her own achievements as an advanced nurse practitioner, emphasising the influential range and significance of this role in ophthalmic care. A pioneering position and job title in the UK and possibly globally, advanced nurse practitioner roles were...

What’s trending? Dec/Jan 2018

A round-up of the eye related hot topics that have been trending on social media over the last few weeks. #scleratattoo Yes, you read that correctly. Scleral tattoos are a relatively new form of extreme body modification. Oddly enough, ‘sclera...

Oculogyric crisis with B12 deficiency

An oculogyric crisis (OGC) is a dystonic movement disorder of the eyes which can last from seconds to hours. Although there is no published diagnostic criteria for OGC, typically the onset is acute, and it is characterised by conjugate upward...

Optimising the ocular surface by managing meibomian gland dysfunction

Meibomian gland dysfunction (MGD) is ubiquitous. Ocular surface inflammation and irritation are prevalent in most ophthalmology clinics: corneal, cataract, glaucoma, oculoplastic, paediatric, vitreo-retinal, medical retina and refractive surgery. These patients also represent roughly one third of those attending for emergency...

Genetic profiling for personalised healthcare solutions in AMD – an update

Age-related macular degeneration (AMD) is a multifactorial condition influenced by genetics and lifestyle factors (Table 1). This article outlines several recent advances in AMD genetics, as well as evolving therapeutic concepts and established practical measures for the treatment and /...

Pigmented paravenous retinochoroidal atrophy

Presentation A 46-year-old Caucasian female was referred to the eye clinic by her local optician following a routine sight test. She was noted to have pigmentary retinal changes in both eyes but was asymptomatic with no visual complaints. At presentation...

First blind yoga classes launched by Sight Scotland

Sight Scotland is proud to announce the launch of its first-ever yoga classes specifically designed for people living with vision impairment. These inclusive sessions offer blind and partially sighted individuals the opportunity to enjoy the physical and mental benefits of...

Conference Report: National Students Ophthalmology Conference 2025

On 10 May, we led the fourth National Student Ophthalmology Conference (NSOC) for the first time in person, in London, with remote accessibility via Zoom, hosting over 130 attendees from the UK and across the globe. The day was packed...