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Experimental Eye Research cover image.

New mouse model of diabetes mellitus

1 April 2014 | | EYE - Vitreo-Retinal
Diabetic retinopathy (DR) is a serious complication of diabetes. It is driven by the loss of pericytes, cells which control vascular function, due to excess formation of sugar alcohols by the enzyme aldose reductase (AR). AR has been shown to...

TowardPi BMizar: Revolutionising Ophthalmic Imaging with Ultra High-Speed Precision

30 March 2026 | Company Profiles, Research & Development
A powerful ophthalmic imaging system that establishes a new benchmark in optical coherence tomography (OCT) and OCT angiography (OCTA). Engineered with an ultra high speed 400 kHz swept source, this device delivers rapid, highly detailed scans of both the anterior...
The Journal of Paediatrics Ophthalmology & Strabismus front cover image.

Recommendation for wide angle fluorescein angiography to diagnose FEVR in NEDSDV

3 April 2026 | | EYE - Paediatrics
Neurodevelopmental disorder with spastic diplegia and visual defects (NEDSDV) is a genetic disease described in 2012 associated with variants in the CTNNB1 gene which encodes beta-catenin. Characteristics include strabismus, reduced visual acuity and familial exudative retinopathy (FEVR). In this study,...

Non-arteritic anterior ischaemic optic neuropathy (NA-AION): a review

1 February 2017 | | EYE - Neuro-ophthalmology
Ischaemic optic neuropathy (ION) is the commonest adult optic neuropathy encountered today in our ageing population, is a common cause of irreversible visual loss and is usually associated with underlying vascular disease. The condition is classified as follows: (a) Anterior...

Cortical blindness

1 August 2014 | | EYE - Cataract, EYE - Cornea, EYE - General, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal
Cortical blindness is a rare but recognised entity. Cerebrovascular accident is a well-known risk factor. We report a case of an 84-year-old lady with bilateral cortical blindness with multiple cardiovascular risk factors. Case report An 84-year-old lady was admitted under...
Journal of Neuro-Ophthalmology cover image.

Comparison of thrombolysis and conservative management in acute retinal ischaemia

1 March 2024 | | EYE - Neuro-ophthalmology
The authors present a retrospective cohort study of individuals presenting with acute, painless, monocular vision loss and diagnosed with acute retinal ischaemia. Reasons for exclusion were iatrogenic aetiology, transient vision loss, missing initial visual acuity data, more than 16 hours...

Bosch-Boonstro-Schaaff optic atrophy syndrome (BBSOAS) NR2F1 mutation

4 December 2023 | | EYE - Neuro-ophthalmology
An experienced ophthalmologist can make an anatomical diagnosis of childhood visual impairment based upon the surgical sieve, i.e., congenital and acquired. But an ophthalmologist cannot work in isolation to make an aetiological diagnosis – one would require the help of...

Is it NAION… Now what?

3 April 2024 | | EYE - Neuro-ophthalmology
Case presentation We present the case and discussion of a 46-year-old Caucasian male who complained of immediate reduced vision following complicated neck dissection including a total laryngopharyngectomy, free flap reconstruction for a T4N3 squamous cell carcinoma (SCC) of the left...

The role of inflammation in the pathophysiology of DMO

1 February 2016 | | EYE - Vitreo-Retinal
Diabetic macular oedema (DMO) is a major cause of visual loss in diabetes, with a complex multifactorial pathogenesis. In the UK alone it is estimated that there are nearly 2.5 million diabetic patients aged over 12 years. Approximately 65,000 of...

Understanding and confronting bacterial endophthalmitis

2 December 2019 | | EYE - Cornea, EYE - Vitreo-Retinal, EYE - General
Abdus Samad Ansari highlights the importance of early recognition of this condition using an unusual presentation. Endophthalmitis is a medical emergency with devastating consequences. Despite adequate treatment, severe cases frequently result in permanent blindness. Endophthalmitis involves inflammation of both the...

The management of chronic central serous chorioretinopathy

1 February 2017 | | EYE - Vitreo-Retinal
Central serous chorioretinopathy (CSCR) is a common retinal disease characterised by one or more serous neurosensory detachments. Patients present with acute onset blurring of vision, metamorphopsia and / or central scotomas. The condition is six times more common in men...

Addressing diabetes-related complications in Tanzania and Eswatini: A comprehensive approach to eye and foot screening

2 October 2025 | | EYE - Imaging
Diabetes is rising globally, particularly in low- to middle-income countries (LMICs), where healthcare systems are under resourced [1,2]. Among its complications, diabetic retinopathy (DR) and diabetic foot disease are preventable yet frequently overlooked [3-6]. These problems often develop together due...