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The fragile p-value

Abdus Samad Ansari explores the limitation of the p-value and the application of the fragility index in clinical trials. Clinical trials and tribulations? The restoration of vision or more purely the gift of sight is an aspect of care that...

COVID-related mucormycosis

The authors report a retrospective case-control study of 73 patients with COVID-19 associated mucormycosis (CAM) between 1st March and 30th May 2021. They compared various factors between the two groups – patients who survived CAM (47 [64%]) and those that...

My Top Five: Tips for organising and delivering a national ophthalmology educational series

Organising a national teaching series is both deeply rewarding and surprisingly complex. It requires more than just good content – it demands a well-thought-out purpose, seamless logistics, strong communication and meaningful evaluation. Over the past year, I had the opportunity...

Intranasal combined dexmedetomidine and intranasal midazolam-ketamine sedation efficacy and associations in childhood strabismus surgery

The aim of this study was to compare the efficacy of intranasal combined dexmedetomidine (D) and intranasal midazolam-ketamine (MK) sedation and their effects on the occurrence of oculocardiac reflex in children’s strabismus surgery. The study recruited 37 children to each...

High-stakes scenarios in retinal vein occlusion: A survey of medico-legal implications

Central retinal vein occlusion (CRVO) is the second most common retinal vascular disease after diabetic retinopathy, and its clinical complexity often intersects with medico-legal scrutiny [1]. Missteps in timely diagnosis, inadequate follow-up or poor documentation can lead to patient harm...

Eye Healthcare: 90 Years of Progress

Eye Healthcare: 90 Years of Progress by Patrick Condon is far more than a historical account, it is a deeply personal, thoughtful and richly illustrated journey through the most transformative decades in ophthalmology, told by one of Ireland’s most respected...

ESASO Course Series Vol. 4 Optical Coherence Tomography

This book, which is the latest volume from the European School for Advanced Studies in Ophthalmology (ESASO) course series, is a revelation and joy to review. This compact volume provides an introduction and an update to the most recent technological...

Predicting ischemic lesion location using perimetry

The authors present a retrospective records review, using the search terms homonymous hemianopia, visual field loss and MRI. Only posterior circulation artery territory ischemic strokes were included. Demographics, stroke details and initial and follow-up with 24-2 SITA Standard perimetry results...

Long-term outcome of ALPI for plateau iris syndrome

The purpose of this study was to evaluate the long-term outcomes of plateau iris syndrome (PIS) patients treated with argon laser peripheral iridoplasty (ALPI) following YAG laser peripheral iridotomy (LPI). Typical ALPI settings were a spot size of 200 to...

The embryology of the eye

Nobody claims to like embryology. At least nobody I know. It has been a neglected part of the curriculum since time immemorial and a vicious cycle occurs in which those with an incomplete understanding fail to appreciate the inherent beauty...

Ophthalmology in the developing world

After the second year of medical school, I spent my summer vacation working as a volunteer for a small Italian non-government organisation (NGO), named HEALTH-AID. As part of my volunteering experience, I joined a team of European doctors, medical students...

How to be ‘appy’ on call: a brief guide to mobile phone applications for the on-call ophthalmologist

One of the unexpected outcomes of the COVID-19 pandemic has been an increased reliance and integration of computer technology within hospital medicine. The need for stricter infection control policies during and after lockdown has seen a boom in technology utilisation....