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The fragile p-value

5 October 2020 | | EYE - General
Abdus Samad Ansari explores the limitation of the p-value and the application of the fragility index in clinical trials. Clinical trials and tribulations? The restoration of vision or more purely the gift of sight is an aspect of care that...

Digital eyecare – enabling better communication between primary and secondary care

3 June 2021 | | EYE - Imaging, EYE - General
Alexander Chiu and his co-authors highlight innovations influencing healthcare advancement and how trainees can get involved. Hospital eye services (HES) were under great pressure to meet demand, even before the COVID-19 pandemic. This pressure has increased with the cancellation and...

Royal Navy Veteran returns to cenotaph 50 years after first parade with Sight Scotland Veterans

19 November 2024 | patient stories, charity, achievements, history, remembrance day
John Finlay, 66, from Dalkeith, served as a Radio Operator in the Royal Navy from 1974 to 1979, stationed at the HMS Cochrane naval base in Rosyth. Now living with sight loss due to diabetes, John is marking an emotional...
Cornea journal cover image.

Adjuvant oral voriconazole or oral ketoconazole for fungal keratitis

1 April 2018 | | EYE - Cornea, EYE - General
This randomised double-blinded trial examined clinical outcomes of 50 patients with severe fungal keratitis treated with either adjuvant oral voriconazole or oral ketoconazole. Inclusion criteria were culture or smear proven fungal ulcers >5mm in maximum diameter, involving >4mm of the...
Ocular immunology and inflammation journal cover image.

ARN in North Africa

1 December 2015 | | EYE - Vitreo-Retinal
Acute retinal necrosis (ARN) is a rare cause of uveitis. This paper aims to outline the clinical features of 12 patients with ARN in a referral centre in Tunisia, North Africa. A retrospective review of case notes was carried out....

Andy Hill (NuVision Biotherapies) discusses recent AOP update to clinical guidelines

8 December 2023 | NuVision, Andy Hill, amniotic membranes, guidelines, AOP, optometrist, outpatient, dry eye, lens
There are currently 600,000 people on the NHS waiting list for ophthalmology treatment, and over 5 million people in the UK currently live with dry eye disease. Here Andy Hill, CEO at NuVision Biotherapies Ltd, discusses a recent update to clinical guidelines and what this means for optometrists, patients, and taxpayers.

Martial arts mum fights for inclusive employment

12 January 2026 | charity, news, patient stories
A visually impaired mum in West Lothian is calling for more accessible and inclusive employment for people with sight loss. Amanda Whitfield (35) recently won medals alongside her five-year-old daughter in mixed martial arts, after taking part in local family...

Update on emerging therapies for age-related macular degeneration

4 December 2023 | | EYE - Vitreo-Retinal
The 23rd European Society of Retina Specialists (EURETINA) Congress, held in Amsterdam, the Netherlands, provided a timely update on anti-complement therapy for geographic atrophy and emerging investigational therapies for neovascular age-related macular degeneration. Anti-complement therapy for geographic atrophy Geographic atrophy...

The paediatric cataract: an overview of the embryology and pathophysiology

5 February 2020 | | EYE - Paediatrics, EYE - Strabismus, EYE - Cataract, EYE - Refractive, EYE - General
In the first of the two articles (see Part 2 here) on paediatric cataracts, Samuel Aryee reviews the aetiology of this condition. Cataracts arise from opacification of the natural transparent lens, which can cause partial or total blindness. Although the...

More sensitive visual acuity test for age-related macular degeneration

1 October 2016 | | EYE - Vitreo-Retinal
Age-related macular degeneration (AMD) is the leading cause of blindness in the developed world. Primarily associated with ageing, genetic factors and lifestyle choices such as smoking also play a contributory role. Patients with early AMD, characterised by the development of...

New survey reveals over half of UK adults expect to experience sight loss in the next 10 years.

18 October 2024 | macular, AMD, Apellis, industry, survey, sight loss
This survey and media article are fully organised and funded by Apellis. New survey reveals over half of UK adults expect to experience sight loss in the next 10 years. Yet more than one in four (29%) of those surveyed...

Genetic therapy gives infants life-changing improvements in sight

24 February 2025 | genetics, gene therapy, Moorfields, paediatrics, research, new, AIPL1, Leber Congenital Amaurosis
Four young children have gained life-changing improvements in sight following treatment with a pioneering new genetic medicine through Moorfields Eye Hospital and UCL Institute of Ophthalmology, with the support of MeiraGTx. The children were born with a severe impairment to...