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Quarter DMEK

This case report describes a novel technique where one quarter of Descemet’s membrane (DM) was transplanted during a quarter-descemet membrane endothelial keratoplasty (DMEK) procedure. DMEK graft was prepared from a 58-year-old corneo-scleral donor after one week in culture. Peripheral DM...

Transfected RPE cells inhibit AMD in rats

Age-related macular degeneration (AMD) is a leading cause of blindness in the elderly. Wet AMD is characterised by choroidal neovascularisation, new vessels into the retina, leading to leakage and tissue damage. Many proangiogenic factors particularly vascular endothelial growth factor (VEGF)...

Macular thickness and visual fields

The authors describe a comparison of spectral domain OCT with Humphrey visual fields (HVF) mean deviation (MD) and pattern standard deviation (PSD), examining the retinal thickness of the macula and circumpapillary retinal nerve fibre layer (RNFL) defects. Seventy-three subjects who...

Mobile phone use with esotropia development

This study analysed clinical characteristics and surgical outcomes in patients with acquired comitant esotropia (ACET) and determined the prevalence of excessive mobile touch screen device use in these patients. This was a retrospective study of 35 patients of which three...

Surgical outcome reporting for exotropic DRS

The authors report the surgical outcomes of patients with exotropic Duane’s retraction syndrome (DRS) in a retrospective study of 73 patients; 67 unilateral cases. Patients had a mean age at surgery of 14.11 years (range 2-33). The left eye was...

Key research and practical information to inform INS care

This ‘tutorial’ format paper aims to translate key research findings and conclusions into practical terms, discuss their clinical utility and introduce a new clinical method that accurately measures the static visual deficits in infantile nystagmus (INS), predicts the improvements that...

Prism adaptation test in acquired non-accommodative esotropia

This study investigated factors related to the increase in prism adapted angle in patients with acquired non-accommodative comitant esotropia (ANAET) who had strabismus surgery based on the results of a short prism adaptation test (PAT) and evaluated their outcomes. Short...

Homonymous hemianopia due to stroke presenting symptoms and lesion locations

A retrospective case notes review was undertaken of patients diagnosed with homonymous hemianopia following a radiologically confirmed stroke. A total of 85 patients were identified by searching an electronic medical records system over an 11-year period. Data were extracted from...

Could idebenone by the solution for treating dominant optic atrophy?

Dominant optic atrophy (DOA) is a disease of the retinal ganglion cells, with no current treatment options. In most cases, DOA is caused by a mutation in the OPA1 gene. The aim of this study was to evaluate the effect...

Clinical features of basic acquired nonaccommodative esotropia requiring surgery

Basic acquired nonaccommodative esotropia (BANAET) is a concomitant esotropia occurring after the age of six months without significant refractive error or accommodative element. Esotropia is similar for both near and distance and children have prior binocular single vision. The purpose...

Correlations of fusional convergence with suppression depth in control of exotropia

This study was undertaken to investigate the differences in fusional convergence during refusion in patients with intermittent exotropia based on suppression depth and exotropia control. This was a cross-sectional study of 25 patients; 15 female and 10 male aged mean...

What plane should be used for ultrasound measurement of the optic nerve sheath diameter?

This prospective observational study aimed to evaluate the differences between optic nerve sheath diameter (ONSD) between the patients’ two eyes and different ultrasound planes (transverse and sagittal). Participants were recruited over a two-year period from a single neurosurgical department. To...