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Retinotopic fMRI reveals visual dysfunction and functional reorganisation in the visual cortex of glaucoma patients

This study investigated the retinotopic functional representation in the visual cortex of mild to moderate primary open-angle glaucoma (POAG) participants and age-matched normal volunteers, using wide-view visual presentation, high-resolution retinotopic stimuli, and high-resolution blood oxygenation level dependent (BOLD) functional magnetic...

Gemini Untwined: treating craniopagus conjoined twins

The authors discuss the successful separation of craniopagus conjoined twins at Great Ormond Street Hospital and the role of the ophthalmologist in such cases. Craniopagus conjoined twins are extraordinarily rare, occurring in only one in 2.5 million births and representing...

Orbis achieves WHO trachoma elimination threshold in Sheka Zone, Southwest Ethiopia

Ahead of World Neglected Tropical Diseases (NTD) Day on 30 January, international eye care charity Orbis has announced that it has achieved the World Health Organisation (WHO) threshold for eliminating trachoma as a public health concern in Sheka Zone, Southwest...

Handbook of Retinal Disease: a case based approach

This book is suitable for all doctors, particularly ophthalmologists, who want to further their knowledge and understanding of retinal pathologies and keep up to date. The case-based format is effective in evoking an interactive approach to differential diagnosis. The tabulation...

Severe conjunctival cicatrisation secondary to chronic glaucoma therapy

The timing of glaucoma filteration surgery during the course of chronic progressive glaucoma remains a contentious issue amongst glaucoma specialists. The vast majority support the use of maximal medical treatment initially to achieve the target pressure. Surgical procedures are only...

Using a tumour registry to investigate optic nerve gliomas

This study is a retrospective comparative analysis. Patients with optic nerve glioma and pilocytic astrocytoma were identified through the Surveillance, Epidemiology and End Results (SEER) cancer registry covering a 42-year period using standardised codes. The following data was extracted: basic...

100 years of insulin

*Joint first authors The centenary of the discovery of insulin is a time to celebrate one of the most significant scientific discoveries of the 20th century. Background Before 1923, Type 1 diabetes mellitus [T1DM] resulted in death from severe ketoacidosis...

Survey of paediatric ophthalmology practice in the US

The purpose of this study was to develop a survey to assess possible solutions for an economic turnaround in paediatric ophthalmology. A 12-item survey was circulated with questions related to practice location, setting and years in practice. Responses were received...

Selective laser trabeculoplasty after medical treatment

Selective laser trabeculoplasty (SLT) is a well-established treatment for open-angle glaucoma (OAG) and ocular hypertension (OHT). This post-hoc secondary analysis of the LiGHT trial extension examined SLT as a secondary intervention after 3 years of protocolised medical therapy in patients...

Meta-analysis of HLA B27 associated acute anterior uveitis

A literature-based meta-analysis was carried out to look at the various clinical features associated with HLA- B27 acute anterior uveitis (AAU). After an extensive search of literature for HLA B27 uveitis was conducted, 735 results were obtained. Twenty-nine articles were...

Herpes zoster ophthalmicus: a clinician’s perspective

Introduction Herpes zoster, commonly known as shingles, is caused by the reactivation of varicella zoster virus (VZV). The term herpes is derived from a Greek work, herpein, which means ‘creeping’ and the word zoster means a belt or a girdle...

Relationship between nocturnal intraocular pressure elevation and diurnal intraocular pressure level in NTG patients

This group studies Korean normo-tension glaucoma (NTG) patients over a 24-hour period to assess if there was a relationship between nocturnal intraocular pressure (IOP) and diurnal IOP. They have previously suggested differences in diurnal IOP may have varying mechanisms of...