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MicroRNA mediate retinoblastoma signal transduction
MicroRNAs (miR) are small non-coding single-stranded RNA molecules, normally 22 nucleotides long. There is a large family of miR that control protein expression by binding to mRNAs, leading to their degradation. One important role of miR is in tumours where...A case of late spontaneous subluxation of in-the-bag intraocular implant
An 82-year-old frail lady was referred by her optometrist with a finding of subluxated implant in the right eye. She had uneventful phacoemulcification with in-the-bag intraocular implant 17 years earlier. There is no history of having had pseudoexfoliation (PXF) or...Foundation Post in Ophthalmology
If you are in your final year of medicine at university, firstly congratulations on making it so far and secondly, you may be wondering how and which jobs to rank highly. If you have found yourself reading this article, then...Contract signed to build Oriel, a state-of-the-art eye health centre
A £300 million contract has been awarded to Bouygues UK to build Oriel, a new eye care, research and education centre in Camden.How to nearly (but not quite) get into ST1 ophthalmology training – some reflections
Ophthalmology is often considered to be an elite, highly competitive specialty, with little room for failure. Candidates and trainees tend to cultivate a certain urbane and confident style, and the bottleneck at ST1 can feel rather intense. The majority of...Diabetic Retinopathy Network laser training programme
The VISION 2020 Diabetic Retinopathy Network (DR-NET) was established in 2014 to tackle the increasing burden of diabetes and diabetic retinopathy (DR) in developing countries [1]. By forming a network of long-term LINK capacity-building partnerships, learning and best practice can...
Managing orbital compartment syndrome
This experimental study using cadaveric models was done to evaluate the surgical technique effective in relieving orbital compartment syndrome. Twelve cadaveric orbits were injected with blood analogue stained with fluorescein. Pressure probes were inserted in superotemporal (advanced 40mm into orbit)...
Perceptual learning treatment for amblyopia
The authors previously conducted a feasibility study examining the potential benefit of a self-administered at-home use of a tablet-based perceptual learning (PL) game. Visual stimuli were presented in various orientations and spatial frequency in a game-play format. This study evaluates...
Care providers view on how to improve care for paediatric conjunctivitis
The authors present a qualitative study. Purposeful sampling was used to recruit physicians or advanced practitioners for paediatric care in emergency, urgent or primary care settings. Semi-structured interviews were either held in-person or by telephone. All participants recruited commonly encountered...
