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Importing iron to the retina
In the retina, iron is particularly critical for the visual phototransduction cascade. In the retinal pigment epithelium (RPE), RPE65 activity leads to 11-cis-retinaldehyde, the photosensitive component of rhodopsin production and iron containing enzymes are necessary for disc replacement in photoreceptor...
Retinitis pigmentosa (RP) associated cystoid macular oedema (CMO)
This is a review article from two units in the UK and Australia, highlighting the supporting evidence of possible pathogenesis and treatment modalities of CMO in RP. The authors proposed that the likely mechanisms for RP-CMO involved the breakdown of...
Surgical effect of limited membrane dissection
Strabismus surgery was performed with minimal dissection of Tenons sheath and minimal tissue manipulation compared to conventional methods for patients with pure horizontal strabismus – to evaluate the effect on surgical outcomes. The study included 54 patients; 52% female. Mean...
Primary intravenous chemotherapy (IVC) for Group D retinoblastoma
A retrospective review is reported of 64 group D retinoblastoma (RB) eyes (52 patients) treated with primary IVC, between 2002 and 2014 from two centres, in the UK and US. The median age at presentation was 11 months, 35 (67%)...
Clinical outcomes of AMT in acute ocular chemical injury
This is a retrospective study of patients from two units in Germany and UK between 1998 and 2008. The ocular chemical burns were classified by Roper-Hall and Dua classifications. A total of 72 eyes of 54 patients aged 37.3 years...
Silent keratitis in failed graft
This study examined rates of asymptomatic keratitis in failed full thickness corneal grafts, which were not picked up clinically preoperatively. During a five year period 53 penetrating keratoplasties (PK) were performed for long-standing graft decompensation with stromal opacity and /...
Lost muscle surgery
The authors present the results of transposition surgery without concomitant lateral rectus weakening in a retrospective review of five cases. Surgery was for large exotropia and marked limitation of adduction after surgical loss of the medial rectus muscle. Mean age...
Dynamics of interocular suppression
The main aim of this study was to determine the development of the depth of interocular suppression in the course of occlusion treatment in amblyopia as well as its correlation with changes in visual acuity. The authors investigated whether presence...
A pattern surgery
The authors describe the efficacy and safety of superior oblique (SO) hang-back recession with A pattern strabismus and SO overaction. A pattern was defined as a difference of >10PD from elevation to depression. SO overaction was graded as +1 to...
Comparison of visual fields between migraine and tension type headaches
The aim of the study was to compare the clinical features and visual fields of patients with migraine without aura and tension type headache. Visual fields were assessed whilst the patients were having an attack of pain and tested using...
Measuring cyclotorsion
The aim of this study was to investigate if different methods of measuring cyclotorsion (synoptophore, KM screen test and single Maddox rod test) produce the same results and if these values are repeatable in adult patients. For the synoptophore, the...
