You searched for "melanoma"
A prospective trial of adjuvant therapy for high-risk melanoma
Patients diagnosed with iris, ciliary body or choroidal melanoma of high-risk tumour cytogenetics (monosomy 3>/= 20% of cells), were treated with adjuvant low-dose dacarbacine (DTIC) and interferon –alpha-2b (IFNA-2b), following primary treatment (enucleation, brachytherapy or resection). DTIC was given intravenously...Identifying life-threatening uveal melanoma: A directed application of general-purpose AI
Uveal melanoma (UM) is a rare but aggressive eye cancer, affecting approximately six people per million annually [1]. Uveal melanoma arises in three locations: the choroid, ciliary body, and iris. As the most common primary intraocular malignancy in adults, UM...Quiz Oct/Nov 2024
History An 83-year-old female was previously treated by surgical excision and plaque brachytherapy for her left conjunctival lesion. She presented to her ophthalmologist with a recurrence some years later and underwent a lid sparing orbital exenteration, which was sent to...Caring for adults with an ocular tumour
1 December 2015
| Bertil E Damato
|
EYE - Vitreo-Retinal
Detection If you screen for an intraocular tumour, dilate the pupil. If the patient is driving, use phenylephrine only. If the patient declines, document this in the casenotes. Don’t forget to look for sentinel vessels, which would indicate a ciliary...
Melanocytoma of the optic disc
1 June 2015
| Lucia Derriman, Sumith Perera
|
EYE - Cataract, EYE - Cornea, EYE - General, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal
Melanocytoma is a heavily pigmented lesion, composed of melanocytes and is a variant of melanocytic naevus. It classically occurs at the optic disc and is usually benign, static and asymptomatic. However, it can occasionally grow and invade the retina or...
Moorfields: Joint Ocular Oncology and Vitreo Retinal Symposium for Nurses and Ophthalmic Health Care Professionals
15 November 2025
Following the success in 2024 of our first Joint Ocular Oncology and Vitreo Retinal Symposium for Nurses and Ophthalmic Health Care Professionals, we are delighted to announce that the symposium will take place again on 15 November 2025. This unique...
A phase 3 randomised trial of nicotinamide for skin cancer chemoprevention
To B3, or not to B3? That was the question asked in this controlled trial in which the authors were able to show that oral nicotinamide (vitamin B3) is able to reduce further skin cancer development in high risk patients....
Imiquimod for lentigo maligna
This is a retrospective review of 12 patients with periocular lentigo maligna treated with topical 5% imiquimod cream. In six patients it was the only treatment, and in the other six it was used following partial excision, cryotherapy or both....NEOS (North Of England Ophthalmological Society) Spring Meeting 2024
23 April 2024
by Matthew Hartley, Trainee, Northern Deanery, UK. In NEOS’ 110th year, the spring meeting was held in Doncaster and centred around ocular oncology and vitreoretinal surgery. The meeting hosts, Umi Harley and Steve Winder from Royal Hallamshire Hospital, arranged a...
