You searched for "limbal"

162 results found

Resurfacing the ocular surface

The ocular surface (OS) is an anatomical and functional unit made of the tear film, the conjunctival, limbal and corneal epithelium, the lacrimal, mucous and meibomian glands and the lids and blink reflex. The tear film is composed of a...

MISS vs. conventional surgery

This was a prospective randomised parallel arm design study for 40 patients. Group 1 consisted of conventional strabismus surgery using the limbal approach and group 2 consisted of minimally invasive strabismus surgery (MISS). Mean age was 21.1±2.73 years for MISS...

New Moorfields stem cell treatment improves vision for untreatable condition

A new breakthrough stem cell treatment for ARK (aniridia-related keratopathy) has seen patients’ vision improve for this previously untreatable rare genetic eye condition in a first-in-human clinical trial at Moorfields Eye Hospital and the UCL Institute of Ophthalmology, published in...

Accuracy of anterior segment OCT in identifying medial and lateral recti muscle insertions in previously operated eyes

In this study, the authors aimed to assess the reliability of anterior segment optical coherence tomography (ASOCT) measurements in strabismus reoperations for locating muscle insertions. This was a prospective observational study of 30 patients (60 previously operated horizontal rectus muscles:...

Chemical injury

You are the on-call ophthalmologist. You receive a call from A&E regarding a 45-year-old man who sustained a chemical injury. He was mixing some cement, when a small amount entered his left eye. He was not wearing any protective goggles....

Conference Report: ARVO 2025 Annual Meeting

The Association for Research in Vision and Ophthalmology (ARVO) 2025 Annual Meeting was held at the Salt Palace Convention Centre in Salt Lake City, US. This prestigious event brought together experts in vision and ophthalmology from around the world for...

Clinical outcomes of AMT in acute ocular chemical injury

This is a retrospective study of patients from two units in Germany and UK between 1998 and 2008. The ocular chemical burns were classified by Roper-Hall and Dua classifications. A total of 72 eyes of 54 patients aged 37.3 years...

Trabeculectomy ab interno (trabectome)

This retrospective study examines the outcome of trabectome surgery in nine phakic patients with Posner-Schlossman syndrome with uncontrolled IOP >30mmgHg. Cytomegalovirus (CMV) DNA was verified by polymerase chain reaction (PCR) in aqueous humour samples. Patients were treated with oral valganciclover...

γδ T cell depletion does not affect fungal keratitis

Fungal keratitis (FK) is a blinding condition prevalent in agricultural areas of countries such as India and China. The fungus enters the cornea and induces an inflammatory response which leads to tissue damage. Neutrophils are the earliest infiltrating immune cells...

MicroRNA inhibits corneal neovascularisation

MicroRNAs (miR) are small non-coding RNA that target mRNA for destruction. MiR target about 30% of the protein coding genes and fine tune their expression. MiR have been shown to be involved in several cellular processes including cell cycle, tissue...

Therapeutic ocular surface medium for persistent corneal epithelial defect

Corneal ulcers and persistent epithelial defects (PEDs) are caused by a variety of different insults to the cornea, which includes limbal epithelial stem cell failure. PED may be resistant to healing with standard therapy such as frequent ointments and /...

Erythropoietin in healing corneal epithelial defects in rabbits

Corneal epithelial defects heal slowly in patients with diabetes, limbal stem cell deficiency and severe chemical burns. Erythropoietin is a glycoprotein hormone that promotes red blood cell proliferation and inhibits apoptosis of erythroid progenitors as well as nonhematopoietic cells. In...