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Herpes zoster ophthalmicus: a clinician’s perspective
Introduction Herpes zoster, commonly known as shingles, is caused by the reactivation of varicella zoster virus (VZV). The term herpes is derived from a Greek work, herpein, which means ‘creeping’ and the word zoster means a belt or a girdle...Burnout: ubiquitous and unavoidable?
Meriam Islam reminds us of the importance of ‘putting our oxygen mask on first’ and avoiding burnout while we progress through our careers. Burnout. It’s a term we hear a lot. What does it mean though? According to Merriam Webster,...New solutions in the prevention and treatment of Acanthamoeba keratitis
The global increase in Acanthamoeba keratitis infections has emphasised the inefficiencies of current treatment and preventative methods, here researchers from the West of Scotland detail a promising new series of compounds that may stem the tide. News headlines detailing horror...ABDO responds to the GOC contact lens consultation
The Association of British Dispensing Opticians (ABDO) welcomes the General Optical Council (GOC) consultation on the definition of contact lens aftercare and verification of contact lens specifications.Behind the curtain: What trainees wish they knew before starting in ophthalmology
As a foundation year doctor, I didn’t expect ophthalmology to feature much in acute medicine or surgery. Yet it kept appearing at the periphery – and when it did, it was often complex and unexpectedly urgent. A confused older patient...Therapy for limbal stem cell deficiency: cell fate after limbal stem cell transplants
“The beauty of scientific research lies in that the search for answers often yields yet more questions.” A large body of evidence points to the corneoscleral limbal location as the repository of putative epithelial stem cells [1]. Thoft proposed the...Resurfacing the ocular surface
The ocular surface (OS) is an anatomical and functional unit made of the tear film, the conjunctival, limbal and corneal epithelium, the lacrimal, mucous and meibomian glands and the lids and blink reflex. The tear film is composed of a...
Differential inhibition of EAU by CTLA4 and IL-6
Cytotoxic T lymphocyte antigen-4 (CTLA4) binds both CD80 and Cd86 and inhibits T lymphocyte activation via CD28. Il-6 is a pleiotropic cytokine that has been associated with many autoimmune conditions including uveitis. Blockade of these molecules by either CTLA4-Ig, a...
Idiopathic orbital pseudotumor as first sign of systemic inflammatory disease
The authors describe four children in whom idiopathic orbital pseudotumor (IOP) was the initial solitary finding with systemic inflammatory disease developing later. Four children were seen over a five-year period. Mean age was 9.75 years (2-14). Three were white and...
Associations with non-attendance for paediatric patients attending eye appointments
In this study the aim was to identify patient demographic, socioeconomic and appointment characteristics associated with missed appointments in paediatric ophthalmology at a tertiary care academic ophthalmology centre and assess appointment reminder method effects. This was a retrospective cross-sectional study...
Serology testing in periocular inflammatory disease
This is a review article of serological tests in thyroid eye disease, IgG4-related disease and myasthenia gravis. The authors provide an overview of the current serology with a brief description of how they relate to the pathogenesis of each condition....
