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Herpes zoster ophthalmicus: a clinician’s perspective

Introduction Herpes zoster, commonly known as shingles, is caused by the reactivation of varicella zoster virus (VZV). The term herpes is derived from a Greek work, herpein, which means ‘creeping’ and the word zoster means a belt or a girdle...

New solutions in the prevention and treatment of Acanthamoeba keratitis

The global increase in Acanthamoeba keratitis infections has emphasised the inefficiencies of current treatment and preventative methods, here researchers from the West of Scotland detail a promising new series of compounds that may stem the tide. News headlines detailing horror...

Spot diagnosis? The white dot syndromes

This review article provides an up-to-date summary of white spot syndromes. The authors explain that the white spot syndromes form a group of inflammatory retinal disorders with distinct lesion distribution and progression patterns. Multimodal imaging has revealed unique phenotypes, enhancing...

Ahmed and Baerveldt glaucoma drainage implant outcomes

This study reports the surgical outcomes of both the Ahmed (AGV) and Baerveldt (BGI) glaucoma drainage implants in a cohort of patients with primary congenital glaucoma over a long follow-up in a single tertiary centre. This was a retrospective study...

Behind the curtain: What trainees wish they knew before starting in ophthalmology

As a foundation year doctor, I didn’t expect ophthalmology to feature much in acute medicine or surgery. Yet it kept appearing at the periphery – and when it did, it was often complex and unexpectedly urgent. A confused older patient...

From Moorfields to Mombasa: The tale of two ophthalmology electives

Ophthalmology fascinates me because the field uniquely combines microsurgical precision with immediate, life-changing outcomes, spanning nine distinct subspecialties that seamlessly integrate medicine, surgery and cutting-edge technology. Put simply, few single organs can match the breadth and depth of pathology the...

Differential inhibition of EAU by CTLA4 and IL-6

Cytotoxic T lymphocyte antigen-4 (CTLA4) binds both CD80 and Cd86 and inhibits T lymphocyte activation via CD28. Il-6 is a pleiotropic cytokine that has been associated with many autoimmune conditions including uveitis. Blockade of these molecules by either CTLA4-Ig, a...

Idiopathic orbital pseudotumor as first sign of systemic inflammatory disease

The authors describe four children in whom idiopathic orbital pseudotumor (IOP) was the initial solitary finding with systemic inflammatory disease developing later. Four children were seen over a five-year period. Mean age was 9.75 years (2-14). Three were white and...

Associations with non-attendance for paediatric patients attending eye appointments

In this study the aim was to identify patient demographic, socioeconomic and appointment characteristics associated with missed appointments in paediatric ophthalmology at a tertiary care academic ophthalmology centre and assess appointment reminder method effects. This was a retrospective cross-sectional study...

Resurfacing the ocular surface

The ocular surface (OS) is an anatomical and functional unit made of the tear film, the conjunctival, limbal and corneal epithelium, the lacrimal, mucous and meibomian glands and the lids and blink reflex. The tear film is composed of a...

Ocular Melanoma UK launches Ocular Melanoma October to shine a light on rare eye cancer

Ocular Melanoma UK (OMUK) the nation’s only charity dedicated exclusively to supporting those affected by ocular melanoma, today launched Ocular Melanoma October – a nationwide campaign highlighting the realities of living with this rare, life-threatening and often misunderstood cancer. Each...

Immunoglobulin G4-related ophthalmic disease – what is it? (Part 2)

Part 2: Clinical presentation and treatment (see part 1 here) Introduction IgG4-related disease (IgG4-RD) is understood to have a vast clinicopathological spectrum; nearly every organ has had reported involvement. Similarly, IgG4-related ophthalmic disease (IgG4-ROD) is known to affect nearly every...