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858 results found

Complement factor B polymorphism and the phenotype of early age-related macular degeneration

The relationship between complement factor H (CFH) and age-related macular degeneration (AMD) is very well known, but other genetic polymorphisms relating to AMD are more poorly understood. This study was designed to investigate the relationship between complement factor B (CFB)...

Effect of refractive corneal surgery on IOP and glaucoma progression

Accuracy of intraocular pressure (IOP) measurement depends on the biomechanical properties of the cornea, including its thickness central corneal thickness (CCT) and keratometry (K). Fifty-six eyes of 56 patients with primary open angle glaucoma (POAG) who had a history of...

A case report showing the natural history of papilloedema

The case report describes a 54-year-old woman who developed increased intracranial hypertension due to chronic dural venous sinus thrombosis in the absence of any significant comorbidity. In the years preceding diagnosis, the patient underwent routine diabetic retinopathy screening; however, gradual...

Is myopia protective against progression of diabetic retinopathy?

This population-based cohort study assessed the association of refractive error with the incidence and progression of diabetic retinopathy (DR); 1562 eyes of 860 patients with diabetes and gradable retinal photographs were included. Baseline data was taken between 2004-2009 and follow-up...

A case of ipsilateral fourth nerve paresis and Horner’s syndrome

The author presents a single case report of an exceptional association between fourth nerve palsy and ipsilateral Horner’s Syndrome. The case is presented alongside magnetic resonance images (MRI) which reveal a mass in the right cavernous sinus. The 54-year-old woman...

Acanthamoeba keratitis

This is a retrospective case series on medical records and corneal photographs of 40 eyes of 35 patients with acanthamoeba keratitis (AK, culture positive or with histopathological diagnosis). The mean age of onset was 30 ±15 years (younger in females)....

New grading description for ROP retinal changes for those meeting termination of vision screening guidelines

This study reports and characterises residual retinal changes seen in eyes that meet criteria for termination of acute retinal screening exams. A novel grading system was used in which retinal exams were graded A to E. ‘A’ was defined as...

Ophthalmic imaging in children

Ophthalmic imaging has in recent years become an integral part of the diagnosis and monitoring of patients. There is now a wide range of instruments available for imaging children and assisting in the provision of detailed clinical information for the...

Portable corneal topography – exploration of a prototype

Ophthalmic imaging devices, such as corneal topographers, are not widespread in the developing world. A small device that connects to a smartphone might be a solution to improve developing nation access to corneal imaging. I recently had the opportunity to...

Paediatric enucleation in a tertiary eye centre in North China, 2001-2015

The authors review the demography and aetiology of paediatric enucleation over a 15-year period. A total of 9307 paediatric ophthalmic inpatients ranging from 0 to 14 years who underwent surgery at Shandong Eye Institute over the past 15 years were...

Deciphering dark retinal patches

We present a case of bilateral extensive dark without pressure (DWP) located outside the retinal vascular arcades in a young female. This retinal finding is benign but, in some instances, darkened retinal patches could be associated with potential sight-threatening conditions....

Unilateral central scotoma following dengue fever

Case report A 16-year-old Caucasian male was referred to the eye casualty at Nottingham University Hospitals NHS Trust by the infectious diseases unit in September 2013. He gave a history of photophobia, pain on eye movements and central blurred vision...