In this study, optical coherence tomography angiography (OCTA) was used to detect the existence of any vascular dysfunction in superficial and deep retinal layers that accompany visual impairment in amblyopic eyes compared to fellow and control eyes. The study included 37 patients aged six to 18 years with anisometropic amblyopia and 373 age and sex matched subjects without amblyopia. Lower visual acuity and higher spherical equivalent refraction were significant in amblyopic versus fellow eyes. Reduced visual acuity was significant for amblyopia verses control eyes. There was a significant decrease in superficial and deep capillary plexus in the superior quadrant in amblyopic eyes compared to fellow and control eyes. This was not seen for other quadrants. There were no differences in mean vascular densities. There is potential that localised defects may be specific to amblyopia eyes. Further studies are needed.
OCT angiography findings in amblyopic eyes
Reviewed by Fiona Rowe
Comparison of retinal vascular structure in eyes with and without amblyopia by OCT angiography.
CONTRIBUTOR
Fiona Rowe (Prof)
Institute of Population Health, University of Liverpool, UK.
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