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This study evaluated and compared measurements of macular vessel density and foveal avascular zone using optical coherence tomography (OCT) angiography in amblyopia eyes and age-matched controls to determine whether results are in agreement with previous studies. This was a cross section comparison study of 49 eyes of 38 children; 17 amblyopes and 21 controls. The mean age for amblyopes was 8.6±2.5 years and for controls was 9.6±2.9 years. There was no significant difference between groups for whole, foveal, parafoveal vessel densities of the superficial capillary plexus and deep capillary plexus measurements. The results indicate that amblyopic eyes and normal eyes have similar retinal capillary plexus densities and foveal avascular zone. They conclude that amblyopia and control eyes have analogous retinal microvasculature.

Analysis of macular vessel density and foveal avascular zone using spectral-domain OCT angiography in children with amblyopia.
Demirayak B, Vural A, Onur IU, et al.
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Fiona Rowe (Prof)

Institute of Population Health, University of Liverpool, UK.

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