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MicroRNA inhibits corneal neovascularisation
MicroRNAs (miR) are small non-coding RNA that target mRNA for destruction. MiR target about 30% of the protein coding genes and fine tune their expression. MiR have been shown to be involved in several cellular processes including cell cycle, tissue...
What effects do repeated Ozurdex implants have in paediatric uveitis?
The aim of this retrospective study was to assess the anatomical and functional results, as well as complications of repeated Ozurdex intravitreal implants in a paediatric (non-infectious) uveitis cohort. Twenty-two eyes (16 patients) received 35 Ozurdex implants over a six...Lessons from an unusual case of syphilis
The rise of syphilis transmission rates over the past two decades has been one of public health’s great puzzles. In the UK, the situation has reached epidemic levels, with a 126% increase between 2013 and 2018 [1]. We present a...
IOOA and DVD surgery
The authors report the results of bilateral modified inferior oblique (IO) transposition considering the equator in seven patients with infantile strabismus syndrome with inferior oblique overaction (IOOA) and dissociated vertical deviation (DVD). Mean age was 4.5 years (2-7) and mean...
Surgical management of high myopia strabismus
This is a small case series of three patients with unilateral or bilateral high myopia with exotropia and hypotropia. Surgery involved nasal loop myopexy between the medial and superior recti muscles with or without lateral rectus recession and / or...
Review of non-arteritic anterior ischaemic optic neuropathy
This article reviews the risk factors, clinical presentation and therapies that have been investigated for non-arteritic anterior ischaemic optic neuropathy (NAAION). Additionally, it provides an update from recent rodent and primate models, offering a new insight into the pathophysiology of...Sensitive cilia – eyelashes in health and disease
In health our eyelashes protect the eyes, but in disease they can disfigure, impair quality of life and threaten vision. In this review the authors discuss aspects of lashes that are relevant to all professionals working near the eyes and...Two cases of acute syphilitic posterior placoid chorioretinitis
Syphilis has re-emerged as a significant public health concern, with the World Health Organization (WHO) estimating that 8 million adults aged 15–49 acquired syphilis in 2022. Untreated syphilis can have severe consequences, including cardiovascular, neurological and ocular complications. Ocular manifestations...
Inferior oblique botulinum toxin as a postoperative test
The authors aimed to evaluate the role of inferior oblique (IO) botulinum toxin (BT) injection as a surgical simulator prior to IO myectomy, i.e. preoperative diplopia test using BT. This was a retrospective review in a single centre over a...Moorfields medical retina: design thinking and service delivery of intravitreal injection service
The Medical Retina service is constantly evolving and developing due to a rise in disease prevalence and treatment evolution. This unique course is especially designed for managers and clinical leaders in medical retina services. The course draws on the strength...It’s not always GCA
Giant cell arteritis (GCA) is an immune mediated granulomatous inflammatory disease that affects muscular middle or large sized arteries. It is considered as a continuation of polymyalgia rheumatica (PMR) when the severity of the disease has increased. It is the...
