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Landmark review of glaucoma treatment and research published by Moorfields-led team
Four world-leading experts, including Hari Jayaram and Gus Gazzard from Moorfields, have combined their knowledge with the findings from over 150 peer-reviewed study publications to produce a landmark paper published in the Lancet.Pituitary adenoma causing compression of the optic chiasm
A 21-year-old girl presented to her general practitioner (GP) with a three-month history of headaches, becoming more frequent and associated intermittent vomiting that did not improve with simple analgesics. There was a strong family history of migraines. She was initially...Patients with low vision benefit from optical sector seeing ‘beyond the eyes’
Patients with low vision are benefitting from an initiative developed by Visualise Training and Consultancy and funded by Thomas Pocklington Trust. Seeing Beyond the Eyes has released its impact report which highlights a huge increase in the number of optical professionals who will now refer patients with low vision to vital support services – up from only 9% to an impressive 96%.Johnson & Johnson announces lead vaccine candidate for COVID-19
Johnson & Johnson has announced the selection of a lead COVID-19 vaccine candidate and the rapid scaling of its manufacturing capacity with the goal of providing global supply of more than one billion doses.ABDO responds to the GOC contact lens consultation
The Association of British Dispensing Opticians (ABDO) welcomes the General Optical Council (GOC) consultation on the definition of contact lens aftercare and verification of contact lens specifications.AOP calls for ‘bold thinking’ in response to DHSC request for new minor and urgent eyecare service
The development of a standard specification for ICBs is welcome but ambition for a national approach ‘should not be sacrificed’.
Chronic lymphocytic leukaemia (CLL) of the lacrimal sac
The authors present a case series of three patients with known CLL, two of which presented with mass and epiphora and one case with epiphora alone. All three patients had initially being diagnosed and were treated for chronic dacryocystitis. Histopathological...
Stromal cell alignment in damaged cornea
Stromal keratocytes are responsible for wound healing in the cornea following damage. Keratocytes at the site of injury become activated and differentiate to myofibroblasts which secrete extracellular matrix (ECM) to close the wound, a response mediated by transforming growth factor...
OCT in peripheral corneal thinning
This small retrospective study used high resolution optical coherence tomography (OCT) Heidelberg Spectralis to identify features which could determine the underlying aetiology of peripheral corneal thinning. Ten patients were included; five with diagnoses of degenerative peripheral thinning; Terrien’s marginal degeneration...
RTP801 as a neuroprotective and axon regenerative treatment
This paper describes the neuroprotective and axon regenerative effects of siRTP801, which is a translatable small-interfering RNA (siRNA) targeting mTOR negative regulator; RTP801, through in-vivo and in-vitro models. In-vivo studies involved an optic nerve crush rat model with intravitreal injections...
Bioengineered human tissue
This is a literature review of the current status of tissue engineering related to ocular and oculoplastic reconstructive surgery. The authors describe the process of bioengineering for tissue reconstruction. The aim is to reproduce functional tissue by the use of...
