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Ethnic disparities in diagnostic sequencing yield
The authors present a systematic review and meta-analysis of the diagnostic yield of next generation sequencing (NGS) for inherited retinal diseases and compare yield from studies performed primarily on patients of European descent from those primarily of East Asian descent....Supporting innovative eye disease research
Newmedica is supporting research into a potential next generation treatment for diabetic retinopathy, reinforcing its commitment as an eye health champion. Working in partnership with charity Sight Research UK, the project is led by Dr Michael O’Hare and his team...The invisible touch: a VISION 2020 LINK with Indonesia
Indonesia’s population, the world’s fourth largest, is spread across 6,000 inhabited islands. Whilst some areas (e.g. Kalimantan, Papua) are relatively sparsely populated, Java is the world’s most densely populated island, with twice the population of the UK in half the...
Expert vs. non expert grading of ROP from digital video images
The primary purpose of this study was to determine whether digital video images of the retina obtained using an indirect ophthalmoscope imaging system could be accurately graded for zone and stage of retinopathy of prematurity (ROP) and the presence of...
Outline of clinical care for healthy newborns with uncomplicated conjunctivitis in the US
The purpose of this study was to explore the current state of clinical care for healthy newborns with uncomplicated ophthalmia neonatorum (ON) using a large electronic health record dataset. Despite the existence of national guidelines for antepartum screening for N....Applanation tonometry in the pandemic era: Are facial masks an obstacle to a correct intraocular pressure measurement?
Current recommendations in the UK advise on wearing any facial covering to prevent the spread of the coronavirus [1]. Whilst this is vital for patient and hospital staff safety, it has led to several changes in the approach to a...Pituitary adenoma causing compression of the optic chiasm
A 21-year-old girl presented to her general practitioner (GP) with a three-month history of headaches, becoming more frequent and associated intermittent vomiting that did not improve with simple analgesics. There was a strong family history of migraines. She was initially...Dr William Mackenzie: a founding figure of modern ophthalmology
The author looks at the career of William Mackenzie and the important role he played in establishing the status of ophthalmology as a recognised medical speciality. There are certain individuals who, blessed with ability and means, are destined to leave...
Strabismus detection by Plusoptix S08
In this study the authors evaluate the accuracy and sensitivity of the Plusoptix S08 photoscreener in detecting strabismus problems in 83 patients aged from six months to 40 years (mean 105 months). A pass was achieved for 25 patients and...
Detection of SO tendon abnormality versus atrophy
This study aimed to evaluate patterns of binocular misalignment in primary gaze, lateral and vertical gaze, and head tilt in patients showing head-tilt dependent hypertropia associated with discontinued superior oblique (SO) tendon but without SO muscle atrophy, versus patients with...In conversation with Robert Henderson
Revolutionary eye treatments offer hope for children facing blindness from CLN2 batten disease. Robert Henderson discusses this, and his use of Heidelberg Engineering’s Spectralis device to better combat it. Pioneering research from Great Ormond Street Hospital (GOSH) and the University...
