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Limitations of next generation sequencing

This is a report of a young female patient with clinically diagnosed retinitis pigmentosa who underwent genetic testing using an inherited retinal disease panel and whole exome sequencing by next generation sequencing (NGS) technology. This approach did not identify any...

Results of STENTube for lacrimal intubation

The STENTube is designed with a varied diameter – a thin central segment with a diameter of 0.86mm and distal tube segments with larger 1.3mm diameter. The thin central segment is exposed at the medial canthus. The distal tubes tamponade...

The Case of Dr Bawa-Garba – Where does the buck stop?

The case of Hadiza Bawa-Garba has left all of us in the UK medical profession with an uncomfortable taste in our mouths. We all know that we work under pressure and we will inevitably make mistakes. We all know that...

Gene therapy: perspectives from young adults with Leber’s congenital amaurosis

The authors present their telephone survey data of 10 patients with a mean age of 24.4 years regarding their opinion on gene therapy for their Leber’s congenital amaurosis. Patients were recruited at the Hospital for Sick Children, Toronto. Of the...

Making sense of the orthoptic assessment

Following the Specialty Trainee article on this topic in the February/March 2020 issue, Joe Smith provides a more detailed breakdown of the orthoptic report. Orthoptists investigate, diagnose and manage a wide variety of patients with varying problems. In this article,...

Should we work together to identify congenital nasolacrimal duct obstruction and otitis media?

The authors present a retrospective medical notes review. The aim of the study was to establish how common tympanostomy tube (T-tube) insertion is in children needing probe and intubation (P&I) for congenital nasolacrimal duct obstruction (CNLDO). All cases of CNLDO...

Can diuretics increase the risk of acute angle closure glaucoma?

Diuretics, used widely in the treatment of hypertension, oedema, heart failure and liver failure, have been implicated in case reports in scientific literature to be linked to bilateral acute angle closure glaucoma (AACG). The aim of this study was to...

RCT to detect palpebral fissure changes after horizontal strabismus surgery

The aim of this prospective randomised controlled trial was to compare changes of vertical palpebral fissure h8 after bilateral lateral rectus (BLR) recession vs unilateral lateral rectus recession/medial rectus muscle scleral plication (RRP) for treatment of intermittent exotropia (IXT). Forty...

From trainee to teacher: Top tips for teaching fellow applications

Getting into ophthalmology training has become increasingly competitive in recent years. In 2025, the competition ratio rose to over 21:1, compared to 3:1 in 2019 [1,2]. Similar trends are seen across other specialties, with over 30,000 doctors applying for just...

Eye drop reminder apps

There are quite a few apps in both the iPhone and Android app stores designed to help patients remember to take their eye drops. The goal here was to select an app suitable to recommend to patients. Ophthalmic specific apps...

Advances in cataract surgery

This article covers recent clinical findings in mydriasis and anaesthesia for cataract surgery, shared by Sathish Srinivasan and Keith Davey at a surgical meeting in Manchester. Towards dropless cataract surgery Day case cataract surgery is the standard of care in...

Treating minor eye conditions in optometry practices: is this a viable model for the future?

The role of the optometrist has expanded in recent years as community eye care services have changed. With the limited scope of general ophthalmic services (GOS) regulations in most parts of the UK, the funding to support additional care has...